Biomedical Imaging

Principles and Applications

Author: Reiner Salzer

Publisher: John Wiley & Sons

ISBN: 1118271920

Category: Technology & Engineering

Page: 448

View: 5455

This book presents and describes imaging technologies that can be used to study chemical processes and structural interactions in dynamic systems, principally in biomedical systems. The imaging technologies, largely biomedical imaging technologies such as MRT, Fluorescence mapping, raman mapping, nanoESCA, and CARS microscopy, have been selected according to their application range and to the chemical information content of their data. These technologies allow for the analysis and evaluation of delicate biological samples, which must not be disturbed during the profess. Ultimately, this may mean fewer animal lab tests and clinical trials.

Biomedical Imaging

Author: Karen M. Mudry,Robert Plonsey,Joseph D. Bronzino

Publisher: CRC Press

ISBN: 0203491408

Category: Medical

Page: 360

View: 474

Comprised of chapters carefully selected from CRC’s best-selling engineering handbooks, volumes in the Principles and Applications in Engineering series provide convenient, economical references sharply focused on particular engineering topics and subspecialties. Culled from the Biomedical Engineering Handbook, Biomedical Imaging provides an overview of the main medical imaging devices and highlights emerging systems. With applications ranging from imaging the whole body to replicating cellular components, the imaging modalities discussed include x-ray systems, computed tomographic systems, magnetic resonance imaging, nuclear medicine, ultrasound, MR microscopy, virtual reality, and more.

Fluorescence Lifetime Spectroscopy and Imaging

Principles and Applications in Biomedical Diagnostics

Author: Laura Marcu,Paul M. W. French,Daniel S. Elson

Publisher: CRC Press

ISBN: 1439861676

Category: Technology & Engineering

Page: 570

View: 8880

During the past two decades, there has been an increasing appreciation of the significant value that lifetime-based techniques can add to biomedical studies and applications of fluorescence. Bringing together perspectives of different research communities, Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics explores the remarkable advances in time-resolved fluorescence techniques and their role in a wide range of biological and clinical applications. Broadly accessible, the book captures the state-of-the-art of fluorescence lifetime metrology and imaging and provides current perspectives on their applications to biomedical studies of intact tissues and medical diagnosis. The text introduces these techniques within the wider context of fluorescence spectroscopy and describes basic principles underlying current instrumentation for fluorescence lifetime imaging and metrology (FLIM). It also covers the wide range of methods, including single channel (point) spectroscopy, fluorescence lifetime imaging microscopy, and single- and multi-photon excitation. Edited by pioneers in this field, with contributions from leading experts, the book includes an overview of complementary techniques that help researchers beginning FLIM research. It offers a comprehensive treatment of fundamental principles, instrumentation, analytical methods, and applications. It also provides an overview of the label-free contrast available from lifetime measurements of tissue autofluorescence and the prospects for exploiting this for clinical applications and biomedical research including drug discovery.

Medical Imaging

Principles and Practices

Author: Mostafa Analoui,Joseph D. Bronzino,Donald R. Peterson

Publisher: CRC Press

ISBN: 1439871027

Category: Medical

Page: 454

View: 7122

The discovery of x-ray, as a landmark event, enabled us to see the "invisible," opening a new era in medical diagnostics. More importantly, it offered a unique undestanding around the interaction of electromagnetic signal with human tissue and the utility of its selective absorption, scattering, diffusion, and reflection as a tool for understanding the physiology, evolution of disease, and therapy. With contributions from world-class experts, Medical Imaging: Principles and Practices offers a review of key imaging modalities with established clinical utilization and examples of quantitative tools for image analysis, modeling, and interpretation. The book provides a detailed overview of x-ray imaging and computed tomography, fundamental concepts in signal acquisition and processes, followed by an overview of functional MRI (fMRI) and chemical shift imaging. It also covers topics in Magnetic Resonance Microcopy, the physics of instrumentation and signal collection, and their application in clinical practice. Highlights include a chapter offering a unique perspective on the use of quantitative PET for its applications in drug discovery and development, which is rapidly becoming an indispensible tool for clinical and research applications, and a chapter addressing the key issues around organizing and searching multimodality data sets, an increasingly important yet challenging issue in clinical imaging. Topics include: X-ray imaging and computed tomography MRI and magnetic resonance microscopy Nuclear imaging Ultrasound imaging Electrical Impedance Tomography (EIT) Emerging technologies for in vivo imaging Contrast-enhanced MRI MR approaches for osteoarthritis and cardiovascular imaging PET quantitative imaging for drug development Medical imaging data mining and search The selection of topics provides readers with an appreciation of the depth and breadth of the field and the challenges ahead of the technical and clinical community ofresearchers and practitioners.

Principles and Advanced Methods in Medical Imaging and Image Analysis

Author: Atam P. Dhawan,H. K. Huang,Dae-Shik Kim

Publisher: World Scientific

ISBN: 9812705341

Category: Medical

Page: 850

View: 2450

Computerized medical imaging and image analysis have been the central focus in diagnostic radiology. They provide revolutionarizing tools for visualization of physiology as well as the understanding and quantitative measurement of physiological parameters. This book provides a unique depth of knowledge from the principles to recent advanced methods in medical imaging instrumentation and techniques as well as multidimensional image analysis and classification methods for research, education and applications in computer-aided diagnostic radiology. Internationally renowned researchers and experts in their respective areas provide detailed description of the basic foundation as well as the most recent developments in medical imaging. This book helps readers to understand theoretical and advanced concepts for important research and clinical applications.

PACS-Based Multimedia Imaging Informatics

Basic Principles and Applications

Author: H. K. Huang

Publisher: Wiley-Blackwell

ISBN: 1118795733

Category: Medical

Page: 672

View: 7717

Thoroughly revised to present the very latest in PACS-based multimedia in medical imaging informatics—from the electronic patient record to the full range of topics in digital medical imaging—this new edition by the founder of PACS and multimedia image informatics features even more clinically applicable material than ever before. It uses the framework of PACS-based image informatics, not physics or engineering principles, to explain PACS-based multimedia informatics and its application in clinical settings and labs. New topics include Data Grid and Cloud Computing, IHE XDS-I Workflow Profile (Integrating the Healthcare Enterprise Cross-enterprise Document Sharing for Imaging), extending XDS to share images, and diagnostic reports and related information across a group of enterprise health care sites. PACS-Based Multimedia Imaging Informatics is presented in 4 sections. Part 1 covers the beginning and history of Medical Imaging, PACS, and Imaging Informatics. The other three sections cover Medical Imaging, Industrial Guidelines, Standards, and Compliance; Informatics, Data Grid, Workstation, Radiation Therapy, Simulators, Molecular Imaging, Archive Server, and Cloud Computing; and multimedia Imaging Informatics, Computer-Aided Diagnosis (CAD), Image-Guide Decision Support, Proton Therapy, Minimally Invasive Multimedia Image-Assisted Surgery, BIG DATA. New chapter on Molecular Imaging Informatics Expanded coverage of PACS and eHR's (Electronic Health Record), with HIPPA compliance New coverage of PACS-based CAD (Computer-Aided Diagnosis) Reorganized and expanded clinical chapters discuss one distinct clinical application each Minimally invasive image assisted surgery in translational medicine Authored by the world's first and still leading authority on PACS and medical imaging PACS-Based Multimedia Imaging Informatics: Basic Principles and Applications, 3rd Edition is the single most comprehensive and authoritative resource that thoroughly covers the critical issues of PACS-based hardware and software design and implementation in a systematic and easily comprehensible manner. It is a must-have book for all those involved in designing, implementing, and using PACS-based Multimedia Imaging Informatics.

Molecular Imaging

Principles and Practice

Author: Ralph Weissleder

Publisher: PMPH-USA

ISBN: 9781607950059

Category: Medical

Page: 1357

View: 3312

The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Molecular Imaging

Basic Principles and Applications in Biomedical Research

Author: Markus Rudin

Publisher: World Scientific

ISBN: 1783263172

Category: Technology & Engineering

Page: 620

View: 7879

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today. This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies. The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. Novel biomedical applications have been included, where appropriate. All the chapters have been thoroughly reworked and the artwork updated. Contents:IntroductionMethodologies:Imaging TechniquesMolecular Reporter Systems, Design of Molecular Imaging ProbesApplications:Drug ImagingImaging Gene ExpressionImaging the Function of Gene ProductsMonitoring of Cell MigrationAppendices Readership: Academics (medicine, pharmacology, biomedical technology) and industry (pharmaceutical, diagnostic, biomedical technology). Keywords:Molecular Imaging;Magnetic Resonance Imaging;Positron-Emission Tomogrpahy;Near-Infrared Fluorescence Imaging;Bioluminescence Imaging;Ultrasound Imaging;Drug Biodistribution and Pharmacokinetics

Medical Infrared Imaging

Principles and Practices

Author: Mary Diakides,Joseph D. Bronzino,Donald R. Peterson

Publisher: CRC Press

ISBN: 1439872503

Category: Medical

Page: 638

View: 6445

The evolution of technological advances in infrared sensor technology, image processing, "smart" algorithms, knowledge-based databases, and their overall system integration has resulted in new methods of research and use in medical infrared imaging. The development of infrared cameras with focal plane arrays no longer requiring cooling, added a new dimension to this modality. Medical Infrared Imaging: Principles and Practices covers new ideas, concepts, and technologies along with historical background and clinical applications. The book begins by exploring worldwide advances in the medical applications of thermal imaging systems. It covers technology and hardware including detectors, detector materials, un-cooled focal plane arrays, high performance systems, camera characterization, electronics for on-chip image processing, optics, and cost-reduction designs. It then discusses the physiological basis of the thermal signature and its interpretation in a medical setting. The book also covers novel and emerging techniques, the complexities and importance of protocols for effective and reproducible results, storage and retrieval of thermal images, and ethical obligations. Of interest to both the medical and biomedical engineering communities, the book explores many opportunities for developing and conducting multidisciplinary research in many areas of medical infrared imaging. These range from clinical quantification to intelligent image processing for enhancement of the interpretation of images, and for further development of user-friendly high-resolution thermal cameras. These would enable the wide use of infrared imaging as a viable, noninvasive, low-cost, first-line detection modality.

Biomedical Optical Imaging Technologies

Design and Applications

Author: Rongguang Liang

Publisher: Springer Science & Business Media

ISBN: 3642283918

Category: Science

Page: 382

View: 9757

This book provides an introduction to design of biomedical optical imaging technologies and their applications. The main topics include: fluorescence imaging, confocal imaging, micro-endoscope, polarization imaging, hyperspectral imaging, OCT imaging, multimodal imaging and spectroscopic systems. Each chapter is written by the world leaders of the respective fields, and will cover: principles and limitations of optical imaging technology, system design and practical implementation for one or two specific applications, including design guidelines, system configuration, optical design, component requirements and selection, system optimization and design examples, recent advances and applications in biomedical researches and clinical imaging. This book serves as a reference for students and researchers in optics and biomedical engineering.

Biomedical Signals, Imaging, and Informatics

Author: Joseph D. Bronzino,Donald R. Peterson

Publisher: CRC Press

ISBN: 1439825289

Category: Medical

Page: 1468

View: 3670

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Biomedical Signals, Imaging, and Informatics, the third volume of the handbook, presents material from respected scientists with diverse backgrounds in biosignal processing, medical imaging, infrared imaging, and medical informatics. More than three dozen specific topics are examined, including biomedical signal acquisition, thermographs, infrared cameras, mammography, computed tomography, positron-emission tomography, magnetic resonance imaging, hospital information systems, and computer-based patient records. The material is presented in a systematic manner and has been updated to reflect the latest applications and research findings.

Basics of Biomedical Ultrasound for Engineers

Author: Haim Azhari

Publisher: John Wiley & Sons

ISBN: 9780470561461

Category: Science

Page: 392

View: 7788

A practical learning tool for building a solid understanding of biomedical ultrasound Basics of Biomedical Ultrasound for Engineers is a structured textbook that leads the novice through the field in a clear, step-by-step manner. Based on twenty years of teaching experience, it begins with the most basic definitions of waves, proceeds to ultrasound in fluids and solids, explains the principles of wave attenuation and reflection, then introduces to the reader the principles of focusing devices, ultrasonic transducers, and acoustic fields, and then delves into integrative applications of ultrasound in conventional and advanced medical imaging techniques (including Doppler imaging) and therapeutic ultrasound. Demonstrative medical applications are interleaved within the text and exemplary questions with solutions are provided on every chapter. Readers will come away with the basic toolkit of knowledge they need to successfully use ultrasound in biomedicine and conduct research. Encompasses a wide range of topics within biomedical ultrasound, from attenuation and eflection of waves to the intricacies of focusing devices, transducers, acoustic fields, modern medical imaging techniques, and therapeutics Explains the most common applications of biomedical ultrasound from an engineering point of view Provides need-to-know information in the form of physical and mathematical principles directed at concrete applications Fills in holes in knowledge caused by ever-increasing new applications of ultrasonic imaging and therapy Basics of Biomedical Ultrasound for Engineers is designed for undergraduate and graduate engineering students; academic/research engineers unfamiliar with ultrasound; and physicians and researchers in biomedical disciplines who need an introduction to the field. This book is meant to be “my first book on biomedical ultrasound” for anyone who is interested in the field.

Modeling & Imaging of Bioelectrical Activity

Principles and Applications

Author: Bin He

Publisher: Springer Science & Business Media

ISBN: 9780387499635

Category: Technology & Engineering

Page: 322

View: 4506

Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in the field and comment on the future direction in this fast developing line of research.

Molecular Sensors and Nanodevices

Principles, Designs and Applications in Biomedical Engineering

Author: John X J Zhang,Kazunori Hoshino

Publisher: William Andrew

ISBN: 1455776769

Category: Science

Page: 512

View: 620

With applications ranging from medical diagnostics to environmental monitoring, molecular sensors (also known as biosensors, chemical sensors, or chemosensors), along with emerging nanotechnologies offer not only valuable tools but also unlimited possibilities for engineers and scientists to explore the world. New generation of functional microsystems can be designed to provide a variety of small scale sensing, imaging and manipulation techniques to the fundamental building blocks of materials. This book provides comprehensive coverage of the current and emerging technologies of molecular sensing, explaining the principles of molecular sensor design and assessing the sensor types currently available. Having explained the basic sensor structures and sensing principles, the authors proceed to explain the role of nano/micro fabrication techniques in molecular sensors, including MEMS, BioMEMS, MicroTAS among others. The miniaturization of versatile molecular sensors opens up a new design paradigm and a range of novel biotechnologies, which is illustrated through case studies of groundbreaking applications in the life sciences and elsewhere. As well as the techniques and devices themselves, the authors also cover the critical issues of implantability, biocompatibility and the regulatory framework. The book is aimed at a broad audience of engineering professionals, life scientists and students working in the multidisciplinary area of biomedical engineering. It explains essential principles of electrical, chemical, optical and mechanical engineering as well as biomedical science, intended for readers with a variety of scientific backgrounds. In addition, it will be valuable for medical professionals and researchers. An online tutorial developed by the authors provides learning reinforcement for students and professionals alike. Reviews of state-of-the-art molecular sensors and nanotechnologies Explains principles of sensors and fundamental theories with homework problems at the end of each chapter to facilitate learning Demystifies the vertical integration from nanomaterials to devices design Covers practical applications the recent progress in state-of-the-art sensor technologies Includes case studies of important commercial products Covers the critical issues of implantability, biocompatibility and the regulatory framework

Issues in Biomedical Engineering Research and Application: 2011 Edition

Author: N.A

Publisher: ScholarlyEditions

ISBN: 1464964556

Category: Technology & Engineering

Page: 1451

View: 6998

Issues in Biomedical Engineering Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biomedical Engineering Research and Application. The editors have built Issues in Biomedical Engineering Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biomedical Engineering Research and Application in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biomedical Engineering Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Medical Imaging: Concepts, Methodologies, Tools, and Applications

Concepts, Methodologies, Tools, and Applications

Author: Management Association, Information Resources

Publisher: IGI Global

ISBN: 1522505725

Category: Medical

Page: 2081

View: 8715

Medical imaging has transformed the ways in which various conditions, injuries, and diseases are identified, monitored, and treated. As various types of digital visual representations continue to advance and improve, new opportunities for their use in medical practice will likewise evolve. Medical Imaging: Concepts, Methodologies, Tools, and Applications presents a compendium of research on digital imaging technologies in a variety of healthcare settings. This multi-volume work contains practical examples of implementation, emerging trends, case studies, and technological innovations essential for using imaging technologies for making medical decisions. This comprehensive publication is an essential resource for medical practitioners, digital imaging technologists, researchers, and medical students.

Design and Applications of Nanoparticles in Biomedical Imaging

Author: Jeff W.M. Bulte,Michel M.J. Modo

Publisher: Springer

ISBN: 3319421697

Category: Medical

Page: 469

View: 9041

This book covers the most recent advances in using nanoparticles for biomedical imaging, including magnetic resonance imaging (MRI), magnetic particle imaging (MPI), nuclear medicine, ultrasound (US) imaging, computed tomography (CT), and optical imaging. Topics include nanoparticles for MRI and MPI, siRNA delivery, theranostic nanoparticles for PET imaging of drug delivery, US nanoparticles for imaging drug delivery, inorganic nanoparticles for targeted CT imaging, and quantum dots for optical imaging. This book serves as a valuable resource for the fundamental science of diagnostic nanoparticles and their interactions with biological targets, providing a practical handbook for improved detection of disease and its clinical implementation.

Imaging in Cellular and Tissue Engineering

Author: Hanry Yu,Nur Aida Abdul Rahim

Publisher: CRC Press

ISBN: 1439848041

Category: Medical

Page: 298

View: 4146

Details on specific imaging modalities for different cellular and tissue engineering applications are scattered throughout articles and chapters in the literature. Gathering this information into a single reference, Imaging in Cellular and Tissue Engineering presents both the fundamentals and state of the art in imaging methods, approaches, and applications in regenerative medicine. The book underscores the broadening scope of imaging applications in cellular and tissue engineering. It covers a wide range of optical and biological applications, including the repair or replacement of whole tissues (such as bone, cartilage, blood vessels, and bladder) and more novel artificially created support systems (such as artificial pancreas and bioartificial liver). Each chapter describes a particular application, relevant optical instrumentation, physical principles governing the imaging method, and strengths and weaknesses of the technique. The book also presents current and emerging data processing procedures. As the field of tissue engineering moves from creating simpler outer body parts to more sophisticated internal organs, researchers need to evaluate and control how well the tissues are engineered and integrated into the living body. Suitable for both experts and newcomers in bioengineering and biomedical imaging, this book shows researchers how to apply imaging techniques to next-generation engineered cells and tissues. It helps them assess the suitability of specific imaging modalities for applications with various functional requirements.

Fundamentals of Medical Imaging

Author: Paul Suetens

Publisher: Cambridge University Press

ISBN: 1108211208

Category: Medical

Page: N.A

View: 8213

This third edition provides a concise and generously illustrated survey of the complete field of medical imaging and image computing, explaining the mathematical and physical principles and giving the reader a clear understanding of how images are obtained and interpreted. Medical imaging and image computing are rapidly evolving fields, and this edition has been updated with the latest developments in the field, as well as new images and animations. An introductory chapter on digital image processing is followed by chapters on the imaging modalities: radiography, CT, MRI, nuclear medicine and ultrasound. Each chapter covers the basic physics and interaction with tissue, the image reconstruction process, image quality aspects, modern equipment, clinical applications, and biological effects and safety issues. Subsequent chapters review image computing and visualization for diagnosis and treatment. Engineers, physicists and clinicians at all levels will find this new edition an invaluable aid in understanding the principles of imaging and their clinical applications.

Medical Devices and Human Engineering

Author: Joseph D. Bronzino,Donald R. Peterson

Publisher: CRC Press

ISBN: 1439825262

Category: Medical

Page: 891

View: 6669

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Medical Devices and Human Engineering, the second volume of the handbook, presents material from respected scientists with diverse backgrounds in biomedical sensors, medical instrumentation and devices, human performance engineering, rehabilitation engineering, and clinical engineering. More than three dozen specific topics are examined, including optical sensors, implantable cardiac pacemakers, electrosurgical devices, blood glucose monitoring, human–computer interaction design, orthopedic prosthetics, clinical engineering program indicators, and virtual instruments in health care. The material is presented in a systematic manner and has been updated to reflect the latest applications and research findings.