Cancer Neurology in Clinical Practice

Neurological Complications of Cancer and its Treatment

Author: David Schiff,Isabel Arrillaga,Patrick Y. Wen

Publisher: Humana Press

ISBN: 3319579010

Category: Medical

Page: 643

View: 4876

This updated edition provides clinicians from various backgrounds and levels of training the information needed to optimally diagnose and manage neurologic complications of the nervous system. Organized into seven sections, this comprehensive volume begins with an overview of diagnostic studies for neurologic complications involving the nervous system. That is followed by sections on metastatic and non-metastatic complications of cancer involving the nervous system, and the interpretation, diagnosis, and management of common neuro-oncologic symptoms. The next section reviews the neurologic complications of cancer therapy, including corticosteroids, radiation therapy, chemotherapy, targeted molecular therapies, immunotherapies, hematopoietic stem cell transplantation, and infections involving the nervous system. The final section focuses on the most important neurologic complications in cancers arising from specific organs. In addition to capturing the latest advancements in the rapidly evolving fields of oncology and cancer neurology, the goal of this resource is to lead clinicians toward prompt diagnosis and intervention in order to improve patient quality of life. "This textbook is a valuable resource for medical oncologists and radiation oncologists, as well as neurologists and neuro-oncologists dealing with these patients. ... Overall, the chapters are well organized, clearly written, fairly balanced, and reasonably up to date. ... I would recommend it as a learning tool to physicians in training (medical students, residents, and fellows) and for more experienced physicians as both a review/ update and a way to gain more in-depth knowledge and insight into the neurologic problems of cancer patients." (John C. Flickinger, International Journal of Radiation Oncology Biology Physics, Vol. 73 (2), 2009) "The general organization of the book is logical and facilitates its practical and everyday use. ... Overall this textbook is very comprehensive and encompasses main neuro-oncological challenges. ... Schiff, Kesari and Wen have edited a very elegant and highly practical textbook, written by recognized authorities in their respective fields, which will be used by a wide range of medical and surgical specialists who are confronted on a daily basis with neurological manifestations of cancer in their practice." (I. Radovanovic and G. Zadeh, British Journal of Cancer, Vol. 100 (6), 2009)

Neurologic Complications of Cancer

Author: Lisa M. DeAngelis,Jerome B. Posner

Publisher: OUP USA

ISBN: 0195366743

Category: Language Arts & Disciplines

Page: 634

View: 3849

The final section addresses several nonmetastatic complications of cancer and includes sections on vascular disease, infections, metabolic and nutritional disorders, side effects of chemotherapy and radiation, and other diagnostic and therapeutic procedures and concludes with a discussion on paraneoplastic syndromes."

Neurological Complications of Systemic Cancer and Antineoplastic Therapy

Author: Herbert B. Newton,Mark G. Malkin

Publisher: CRC Press

ISBN: 1420020498

Category: Medical

Page: 648

View: 1390

Neurological Complications of Systematic Cancer and Antineoplastic Therapy provides an in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses less common complications such as paraneoplastic disorders and neoplastic plexopathy. Highlights include: The pathophysiology and molecular biology of cancer and the metastatic phenotype Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses Metabolic and nutritional disorders CNS infections Neurological complications of immunotherapy and bone marrow transplants Additional chapters review problems related to each specific tumor type, such as breast, lung, and colorectal, as well as gynecological cancer, genitourinary cancer, and malignant melanoma. The book also discusses neurological complications related to treatments such as radiation and chemotherapy. Bringing clinical trial knowledge from the bench to the bedside, this volume is an essential reference for the practicing oncologist and neurologist.

Cancer Neurology in Clinical Practice

Author: David Schiff,Patrick Wen

Publisher: Springer Science & Business Media

ISBN: 1592593178

Category: Medical

Page: 464

View: 5140

In Cancer Neurology in Clinical Practice, leading neuro-oncologists from around the world comprehensively review the neurologic symptoms that cancer patients experience, and show how they should be interpreted and evaluated. Organized by both symptom and organ, the book carefully describes each diagnostic neurologic entity-from symptomatology to diagnostic studies to management and prognosis-and presents each major type of cancer in terms of it neurologic problems and how they should be handled. The role of surgery, radiation, chemotherapy, and other palliative measures are considered for each type of problem. Multidisciplinary and up-to-date, Cancer Neurology in Clinical Practice explains to the busy physicians treating cancer patients the latest findings in neuro-oncology that will help them to focus their differential diagnosis, diagnostic strategy, and treatment plan for the cancer patient with neurologic symptoms and findings.

Neurologic Complications of Cancer Therapy

Author: Eudocia Quant Lee, MD, MPH,David Schiff, MD,Patrick Y. Wen, MD

Publisher: Demos Medical Publishing

ISBN: 1617050199

Category: Medical

Page: 200

View: 4591

Neurologic side effects of cancer therapy can inhibit treatment, can be dose-limiting and can diminish quality-of-life. Neurotoxicity related to cancer therapy is a common problem in oncology practice and in clinical neurology. Recognition of neurologic complications of anticancer therapy is necessary due to potential confusion with metastatic disease, paraneoplastic syndromes or comorbid neurologic disorders that do not require reduction or discontinuation of therapy. Neurologic Complications of Cancer Therapy provides comprehensive coverage of the recognition and management of neurologic symptoms related to cancer therapy. The book includes sections on systemic therapy discussed by both agent and adverse event. The section on adverse events is particularly valuable to clinicians, allowing them to consult by symptom in cases where multiple agents have been administered and the source of the complication is uncertain. The systemic therapy section includes coverage of immunologic agents, biologics, and targeted therapies. The book also features sections on the complications of radiation therapy, complications of surgery and high-dose chemotherapy, and stem cell transplantation. Neurologic Complications of Cancer Therapy Features: A widely recognized team of editors Systemic therapy covered by therapeutic agent and by adverse event, enabling a "problem-oriented" approach for the clinician Coverage of newer modalities including immunologic agents, biologics, and targeted therapies Complete sections on complications of radiation therapy, surgery, high-dose chemotherapy, and stem-call transplantion

Neuro-oncology

Author: Jeremy Rees,Patrick Y. Wen

Publisher: Elsevier Health Sciences

ISBN: 0750675160

Category: HEALTH & FITNESS

Page: 461

View: 6447

Neuro-Oncology-a new title in the Blue Books of Practical Neurology series-is a concise and clinically applicable guide to this dynamic subspecialty. Jeremy Rees, PhD, MRCP and Patrick Y. Wen, MD present the most current information on the treatment and management of primary CNS tumors, secondary brain tumors, and the neurological complications of other cancers and their therapies in a format and scope appealing to both the general neurologist and the subspecialist. Access comprehensive coverage of treatment for adult and pediatric conditions-including tumors of the spinal cord as well as the brain. Find coverage of recent advances easily thanks to the emphasis on the latest clinical and laboratory findings and their implications for clinical management and treatment. Apply the possibilities and outcomes of neuro-oncologic surgery within the context of neurologic practice. Address the neurologic complications of cancer and its treatment as well as of primary and secondary tumors. Tap into the global perspectives of experts from all around the world for a multi-disciplinary approach to practice.

Oral Complications of Cancer and Its Management

Author: Andrew Davies,Joel Epstein

Publisher: Oxford University Press

ISBN: 0199543585

Category: Medical

Page: 312

View: 9418

Oral complications are hugely important for those treating cancer patients, either as an indication of disease or as a symptom of the disease. This is the first book to focus on this unique area of cancer care, providing international, evidence-based, clinical guidance for the whole team involved in treating the cancer patient with oral problems.

Neurologic Complications of Critical Illness

Author: Eelco F. M. Wijdicks

Publisher: Oxford University Press, USA

ISBN: 9780195140798

Category: Medical

Page: 415

View: 6089

This second edition of the definitive volume on the diagnosis and management of neurologic complications during critical illness has been thoroughly revised and expanded to bring the book up-to-date. Important features include information on neurologic complications in organ transplant recipients, muscle and nerve injury in critical illness, status epilepticus, cerebral edema, multisystem trauma including cervical spine and traumatic brain injury, and prognosis. The second edition includes entirely new chapters on: *Evaluation of coma focused on structural causes *Neurologic complications in the critically ill pregnant patient *Ethical issues and practical problems with withdrawl of life support New material on: *Pathophysiological mechanisms (set off in different type so that these sections can be read separately) *Neuroimaging studies (including the addition of two pages of full color plates) *Electrophysical examples including EEG, evoked potentials, and nerve conduction studies The first edition (published under the title Neurology of Critical Illness by F.A. Davis in 1995) was highly praised as a concise, practical volume introducing this new and rapidly-evolving specialty that focuses on the care of patients in general medicine and sugical intensive care units with significant disease of the nervous system, either as a primary event or secondary to involvement of organs outside the nervous system. The book is intended for neurologists, intensivists, anesthesiologists, pulmonologists, neurosurgeons, neurology and ICU nurses, and transplant surgeons.

Navigating Life with a Brain Tumor

Author: Lynne P. Taylor,Alyx B. Porter Umphrey,Diane Richard

Publisher: Oxford University Press

ISBN: 0199897794

Category: Health & Fitness

Page: 211

View: 1489

Navigating Life with a Brain Tumor is a guide for anyone affected by brain tumors and their associated conditions-patients, family members, friends, and caregivers. Providing readily accessible information and real-world encouragement to people living with primary and metastatic brain tumors and their caregivers, this book discusses the basics of brain tumors, types of tumors, management of different tumors, related symptoms, treatments and side effects, the role of medical team members, and coping strategies from initial diagnosis throughout the course of the illness. At the same time, it also offers practical suggestions on symptom management and lifestyle modification, as well as real-life anecdotes and advice from both patients and family members and friends who are experiencing this diagnosis.

Neurologic Aspects of Systemic Disease

Author: José Biller,José M. Ferro

Publisher: Newnes

ISBN: 0702044334

Category: Medical

Page: 736

View: 3600

Systemic disease involves several parts of the body or the complete system. Neurologic Aspects of Systemic Disease, a two-part volume in the Handbook of Clinical Neurology series, focuses on the specific neurologic aspects of systemic disease. Part 2 includes coverage of gastrointestinal and hepatobiliary, endocrinologic, and metabolic diseases, as well as nutritional, environmental, and hematologic disorders. Each chapter provides a complete introduction to the neurologic aspect and provides the best known diagnostic and treatment practices. The collection is a valuable and trusted resource for clinical neurologists, research neurologists, neuroscientists, and general medical professionals: a first stop for a focused review of the state of the art for understanding the neurologic impact of each covered disease. A comprehensive introduction and overview of the neurologic aspects of systemic disease Part 2 covers of gastrointestinal/hepatobiliary, endocrinologic, and metabolic diseases and nutritional, environmental, and hematologic disorders Each chapter focuses on the neurologic aspects related to a specific disease presentation

Neurologic Complications of Cancer Therapy

Author: Eudocia Quant Lee, MD, MPH,David Schiff, MD,Patrick Y. Wen, MD

Publisher: Demos Medical Publishing

ISBN: 1617050199

Category: Medical

Page: 200

View: 7667

Neurologic side effects of cancer therapy can inhibit treatment, can be dose-limiting and can diminish quality-of-life. Neurotoxicity related to cancer therapy is a common problem in oncology practice and in clinical neurology. Recognition of neurologic complications of anticancer therapy is necessary due to potential confusion with metastatic disease, paraneoplastic syndromes or comorbid neurologic disorders that do not require reduction or discontinuation of therapy. Neurologic Complications of Cancer Therapy provides comprehensive coverage of the recognition and management of neurologic symptoms related to cancer therapy. The book includes sections on systemic therapy discussed by both agent and adverse event. The section on adverse events is particularly valuable to clinicians, allowing them to consult by symptom in cases where multiple agents have been administered and the source of the complication is uncertain. The systemic therapy section includes coverage of immunologic agents, biologics, and targeted therapies. The book also features sections on the complications of radiation therapy, complications of surgery and high-dose chemotherapy, and stem cell transplantation. Neurologic Complications of Cancer Therapy Features: A widely recognized team of editors Systemic therapy covered by therapeutic agent and by adverse event, enabling a "problem-oriented" approach for the clinician Coverage of newer modalities including immunologic agents, biologics, and targeted therapies Complete sections on complications of radiation therapy, surgery, high-dose chemotherapy, and stem-call transplantion

Mayo Clinic Neurology Board Review: Clinical Neurology for Initial Certification and MOC

Author: Kelly D Flemming,Lyell K Jones

Publisher: Oxford University Press

ISBN: 0190244933

Category: Medical

Page: 736

View: 5976

This print edition of "Mayo Clinic Neurology Board Review: Clinical Neurology for Initial Certification and MOC" comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Written specifically for anyone preparing to recertify for the Neurology Boards, or even those taking the exam for the first time, this comprehensive board review guide is everything needed in an easy to read, and beautifully presented, text. With extensive neuroimaging, illustrations, and neuropathology included, this book eliminates the need for obtaining multiple resources to study for the neurology board examination with high-yield information emphasized to highlight key facts. The book is divided into the basic sciences in Part 1 and clinical neurology in Part 2. It features short, easy-to-read chapters to help the busy resident, fellow, and clinician "on the run." In addition to those people preparing to take, or recertify for, the neurology boards, it will also be useful to medical students and residents rotating through neurology or for the generalist with an interest in reviewing neurology.

Handbook of Brain Tumor Chemotherapy

Author: Herbert B. Newton

Publisher: Elsevier

ISBN: 9780080455938

Category: Medical

Page: 586

View: 565

Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including “targeted agents. The Handbook of Brain Tumor Chemotherapy reviews the state-of-the-art of chemotherapy development and clinical treatment of patients with this devastating disease. Handbook of Brain Tumor Chemotherapy offers a unique cutting-edge compendium of basic science and clinical information on the subject of brain tumor chemotherapy, reviewing what has been accomplished thus far and how the field will continue to evolve with the development of more specific and efficacious chemotherapeutic agents. This book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. Provides the most up to date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics, for the treatment of brain tumors Broadly appeals to anyone interested in the field of Neuro-Oncology and in the treatment of patients with brain tumors Useful to clinicians interested in a thorough overview of the use of chemotherapy in patients with a broad range of brain tumors as well as serving as a source of background information to basic scientists and pharmaceutical researchers with an interest in the molecular therapeutics of brain tumors

Cardio-Oncology

The Clinical Overlap of Cancer and Heart Disease

Author: Gretchen G. Kimmick,Daniel J. Lenihan,Douglas B. Sawyer,Erica L. Mayer,Dawn L. Hershman

Publisher: Springer

ISBN: 3319430963

Category: Medical

Page: 319

View: 9685

Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics: • Cardiac complications in patients receiving cancer therapy • The treatment of cancer in patients with cardiovascular disease • The treatment of cardiovascular disease in patients with cancer When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.

Neurology in Clinical Practice: The neurological disorders

Author: Walter George Bradley

Publisher: Taylor & Francis

ISBN: 9789997625892

Category: Nervous system

Page: 2545

View: 2335

New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.

Differential Diagnosis in Neuro-oncology

Author: Jerzy Hildebrand,Michael Brada

Publisher: Oxford University Press, USA

ISBN: N.A

Category: Medical

Page: 298

View: 5491

Most neurological lesions in cancer patients are progressive, have a profound influence on the quality of life and are life threatening. Management of the situation requires rapid identification of the nature and location of the problem as the treatment outcome depends as much on the speed of diagnosis as on the subsequent therapy. While modern neuroimages provides invaluable clues to the diagnosis, they need to be interpreted in the light of clinical data. The clinical examination remains the cornerstone of the differential diagnosis of neurological lesions affecting the cancer patient. Neurological disorders are a consequence not only of primary tumours of the central and peripheral nervous system but also of systemic malignancy. One in five patients with disseminated malignancy develop neurological complications other than neurogenic pain. The majority of neurological problems are a direct consequence of metastatic disease or the result of metabolic disorders; however, some disorders are due to anti-neoplastic treatments or the administration of drugs. The incidence of CNS infections and vascular lesions is also increased in malignant disease, and a small proportion of neurological disorders are paraneoplastic, resulting from a remote effect of cancer on the nervous system. This book, written by a neurologist and an oncologist, aims to help the clinician to identify and locate the underlying neurological lesion in a cancer patient, and to make a quick therapeutic decision. Diagnostic and therapeutic algorithms are included with an emphasis on the more common and potentially treatable conditions. It should be read by neuro-oncologists, medical oncologists, radiation therapists, neurosurgeons and all those involved in the management of cancer patients.

Handbook of Neuro-Oncology Neuroimaging

Author: Herbert B. Newton

Publisher: Academic Press

ISBN: 0128011688

Category: Medical

Page: 864

View: 6622

Remarkable progress in neuro-oncology due to increased utilization of advanced imaging in clinical practice continues to accelerate in recent years. Refinements in magnetic resonance imaging (MRI) and computed tomography (CT) technology, and the addition of newer anatomical, functional, and metabolic imaging methods, such as MRS, fMRI, diffusion MRI, and DTI MRI have allowed brain tumor patients to be diagnosed much earlier and to be followed more carefully during treatment. With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this second edition of the Handbook of Neuro-Oncology Neuroimaging is so relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuro-Imaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the first edition, and in addition will feature several new important chapters covering diverse topics such as advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. It will also serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. Provides a background to translational research and the use of brain imaging for brain tumors Contains critical discussions on the potential and limitations of neuroimaging as a translational tool for the diagnosis and treatment of brain tumor and neuro-oncology patients Presents an up-to-date reference on advanced imaging technologies, including computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), as well as the recent refinements in these techniques

Neuropsychology of Cancer and Oncology

Author: Chad A. Noggle,Raymond S. Dean,Gary Johnson, MD

Publisher: Springer Publishing Company

ISBN: 0826108172

Category: Medical

Page: 467

View: 5555

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Palliative Care in Neurology

Author: Raymond Voltz

Publisher: Oxford University Press, USA

ISBN: 9780198508434

Category: Medical

Page: 448

View: 1810

'This book will be a valuable resource for neurologists, providing them with a wealth of information about symptom control, communication, end-of-life care and the ethical issues that accompany terminal illness. It should be compulsory reading for all neurologists in training... The editors are to be congratulated on a job well done.' -IAHPC WebsitePalliative care is the duty of every neurologist: however, to date, this has not been a standard feature of neurological practice or training. This book helps define a new field, namely palliative care in neurology. It brings together all necessary information for neurologists caring for a patient with advance disease.Palliative care is an approach to the management of patients with life-threatening illness that attempts to enhance comfort, relieve psychosocial and spiritual distress, assure respect for decision making, provide support for the family, and prepare the patient and family for the end of life. This unique book covers each of the many dimensions of palliative care as they relate to patients with advanced neurological disorders. Basic principles of palliative care and specific ethical issues (such as euthanasia, food and hydration and advance directives) are covered. The needs of populations with specific neurological disorders are described and the management of symptoms that are common to all is explored in detail. Each chapter introduces its topic using a case report that may be used directly for teaching purposes. The authors have put together an invaluable resource, which lays the foundation for further research in the field.Readership: Neurologists both in practice and academia, palliative care physicians.

Rare Genitourinary Tumors

Author: Lance Pagliaro

Publisher: Springer

ISBN: 3319300466

Category: Medical

Page: 367

View: 3070

Rare Genitourinary Tumors offers the reader an up-to-date discussion of the less common neoplasms affecting the urinary tract and reproductive organs. Each authoritative chapter provides and in-depth discussion that is frequently not found in other urologic oncology textbooks. A valuable reference for urologists, oncologists, and those in specialty training, this volume provides ready access to information on etiology, incidence, risk factors, diagnosis, prognosis, insights from molecular pathology and, where applicable, data from clinical trials. The practical treatment guidelines included for each tumor type are written by experts and fully referenced.