Genetics

Author: Daniel L. Hartl,Maryellen Ruvolo

Publisher: Jones & Bartlett Publishers

ISBN: 1449626114

Category: Science

Page: 860

View: 8925

The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.

Principles of Genome Analysis and Genomics

Author: Sandy B. Primrose,Richard Twyman

Publisher: John Wiley & Sons

ISBN: 144431128X

Category: Science

Page: 288

View: 4839

With the first draft of the human genome project in the public domain and full analyses of model genomes now available, the subject matter of 'Principles of Genome Analysis and Genomics' is even 'hotter' now than when the first two editions were published in 1995 and 1998. In the new edition of this very practical guide to the different techniques and theory behind genomes and genome analysis, Sandy Primrose and new author Richard Twyman provide a fresh look at this topic. In the light of recent exciting advancements in the field, the authors have completely revised and rewritten many parts of the new edition with the addition of five new chapters. Aimed at upper level students, it is essential that in this extremely fast moving topic area the text is up to date and relevant. Completely revised new edition of an established textbook. Features new chapters and examples from exciting new research in genomics, including the human genome project. Excellent new co-author in Richard Twyman, also co-author of the new edition of hugely popular Principles of Gene Manipulation. Accompanying web-page to help students deal with this difficult topic at www.blackwellpublishing.com/primrose

Principles and Practice of Gynecologic Oncology

Author: Richard R. Barakat,Maurie Markman,Marcus Randall

Publisher: Lippincott Williams & Wilkins

ISBN: 078177845X

Category: Medical

Page: 1072

View: 7355

Providing comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies, this edition has 30 percent new contributing authors and new material. A companion Web site offers a fully searchable text.

Principles and Practice of Clinical Cardiovascular Genetics

Author: Dhavendra Kumar,Perry Elliott

Publisher: Oxford University Press, USA

ISBN: 0195368959

Category: Medical

Page: 600

View: 7772

Consisting of contributions from experts in all specialties of cardiovascular genetics and applied clinical cardiology, Principles and Practice of Clinical Cardiovascular Genetics serves as the comprehensive volume for any clinician or resident in cardiology and genetics. Each chapter provides a detailed and comprehensive account on the molecular genetics and clinical practice related to specific disorders or groups of disorders, including Marfan syndrome, thoracic and abdominal aortic aneurysms, hypertrophic, dilated and restrictive cardiomyopathies and Arrhythmogenic right ventricular cardiomyopathy, as well as many others. All sections comprehensively address cardiovasuclar genetic disorders, beginning with an introduction and including separate sections on the disease's basic biological aspects, specific genetic mechanisms or issues, clinical aspects, genetic management (e.g., genetic diagnosis, risk assessment, genetic counseling, genetic testing), and clinical management issues. The final section exclusively addresses the management of cardiovascular genetic disorders, specifically considering stem cell therapy, genetic counseling, pharmacogenomics and the social and ethical issues surrounding disease treatment.

Principles of Genetic Toxicology

Author: D. Brusick

Publisher: Springer Science & Business Media

ISBN: 9780306425325

Category: Medical

Page: 284

View: 6599

The field of genetic toxicology has gone through remarkable development in the seven years since the appearance of the first edition of Principles of Genetic Toxicology. One branch of toxicology research, chemical mutagenesis, has been elucidated and expanded as a result of increased effort, testing, and the sharing of data. This expansion has occurred not only in the industrialized countries, but also in countries that are comparatively less advanced in scientific implementation. These developing countries have taken advan tage of the basic practical methods that were so well described in the first edition of this work. It is significant to note how many centers have been established throughout the world and are now studying the basic concepts and applying them to practical problems such as the detection of genetic effects caused by exposure to chemicals. In fact, there are now toxicology training centers in twelve countries. Genetic toxicology, in addition to being investigated as a science unto itself, has been taught to people in the applied fields so that these techniques may be put to use in solving other biological problems. For these reasons, it is most useful to have an update of the basic methods and their development. Dr. Brusick should be congratulated for doing such an excellent job of assembling a text that will be worthwhile to any researcher who is interested in the principles of genetic toxicology. Alexander Hollaender Council for Research Planning in Biological Sciences, Inc. Washington, D. C.

Gentechnologie für Einsteiger

Author: T. A. Brown

Publisher: Spektrum Akademischer Verlag

ISBN: 9783827428684

Category: Science

Page: 298

View: 1869

Gentechnologie für Einsteiger hat sich weltweit als leicht verständliche Einführung in dieses wichtige und spannende Wissenschaftsgebiet bewährt. Die sechste Auflage bleibt dem Grundkonzept früherer Auflagen treu, widmet sich aber auch neuen, wachsenden Forschungsfeldern. Das Buch bleibt damit ein unentbehrlicher Leitfaden für Studierende in den Biowissenschaften und ihren zahlreichen Teilgebieten. Es eignet sich auch bestens als Einführung für alle, die sich in ihrem Beruf mit den Grundlagen des Themas vertraut machen müssen.

Principles of Medical Genetics

Author: Thomas D. Gelehrter,Francis S. Collins,David Ginsburg

Publisher: Lippincott Williams & Wilkins

ISBN: 9780683034455

Category: Medical

Page: 410

View: 8058

European Philosophy of Science - Philosophy of Science in Europe and the Viennese Heritage

Author: Maria Carla Galavotti,Elisabeth Nemeth,Friedrich Stadler

Publisher: Springer Science & Business Media

ISBN: 331901899X

Category: Science

Page: 403

View: 2641

This volume combines the theoretical and historical perspective focusing on the specific features of a European philosophy of science. On the occasion of the 20th anniversary of the Institute Vienna Circle the Viennese roots and influences will be addressed, in addition. There is no doubt that contemporary philosophy of science originated mainly in Europe beginning in the 19th century and has influenced decisively the subsequent development of globalized philosophy of science, esp. in North America. Recent research in this field documents some specific characteristics of philosophy of science covering the natural, social, and also cultural sciences in the European context up to the destruction and forced migration caused by Fascism and National Socialism. This European perspective with the integration of history and philosophy of science and the current situation in the philosophy of science after the transatlantic interaction and transformation, and the “return” after World War II raises the question of contemporary European characteristics in the philosophy of science. The role and function of the renowned Vienna Circle of Logical Empiricism and its impact and influence on contemporary philosophy of science is on the agenda, too. Accordingly, the general topic is dealt with in two parallel sessions representing systematic-formal as well as genetic-historical perspectives on philosophy of science in a European context up to the present.​

Principles of Mathematical Analysis

Author: Walter Rudin

Publisher: McGraw-Hill Publishing Company

ISBN: 9780070856134

Category: Mathematics

Page: 342

View: 544

The third edition of this well known text continues to provide a solid foundation in mathematical analysis for undergraduate and first-year graduate students. The text begins with a discussion of the real number system as a complete ordered field. (Dedekind's construction is now treated in an appendix to Chapter I.) The topological background needed for the development of convergence, continuity, differentiation and integration is provided in Chapter 2. There is a new section on the gamma function, and many new and interesting exercises are included. This text is part of the Walter Rudin Student Series in Advanced Mathematics.

Leibel and Phillips Textbook of Radiation Oncology - E-Book

Expert Consult

Author: Richard Hoppe,Theodore L. Phillips,Mack Roach

Publisher: Elsevier Health Sciences

ISBN: 1437737757

Category: Medical

Page: 1664

View: 6995

Stay on top of the latest scientific and therapeutic advances with the new edition of Leibel and Phillips Textbook of Radiation Oncology. Dr. Theodore L. Phillips, in collaboration with two new authors, Drs. Richard Hoppe and Mack Roach, offers a multidisciplinary look at the presentation of uniform treatment philosophies for cancer patients emphasizing the "treat for cure" philosophy. You can also explore the implementation of new imaging techniques to locate and treat tumors, new molecularly targeted therapies, and new types of treatment delivery. Supplement your reading with online access to the complete contents of the book, a downloadable image library, and more at expertconsult.com. Gather step-by-step techniques for assessing and implementing radiotherapeutic options with this comprehensive, full-color, clinically oriented text. Review the basic principles behind the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, and more. Use new imaging techniques to anatomically locate tumors before and during treatment. Apply multidisciplinary treatments with advice from experts in medical, surgical, and radiation oncology. Explore new treatment options such as proton therapy, which can facilitate precise tumor-targeting and reduce damage to healthy tissue and organs. Stay on the edge of technology with new chapters on IGRT, DNA damage and repair, and molecularly targeted therapies.

Principles of Exposure Measurement in Epidemiology

Collecting, evaluating and improving measures of disease risk factors

Author: Emily White,Bruce K Armstrong,Rodolfo Saracci

Publisher: OUP Oxford

ISBN: 0191004928

Category: Medical

Page: 440

View: 7376

The second edition of this internationally acclaimed title is the ideal handbook for those involved in conducting epidemiological research. The objective of most epidemiological studies is to relate exposure to putative causal agents to the occurrence of a particular disease. The achievement of this objective depends critically on accurate measurement of exposure. This book reviews principles and techniques that can be applied to measuring a wide range of exposures, including demographic, behavioral, medical, genetic, and environmental factors. The book covers questionnaire design, conducting personal interviews, abstracting information from medical records, use of proxy respondents, and measurements from human specimens and in the environment. It gives a comprehensive account of measurement error and the estimation of its effects, and the design, analysis, and interpretation of validity and reliability studies. Emphasis is given to the ways in which the validity of measurements can be increased. Techniques to maximize participation of subjects in epidemiological studies are discussed, and ethical issues relevant to exposure measurement are outlined.

Genetic Governance

Health, Risk and Ethics in a Biotech Era

Author: Robin Bunton,Alan Petersen

Publisher: Routledge

ISBN: 1134258895

Category: Social Science

Page: 10

View: 5610

Ethical and practical issues around genetic research are of major international concern, both in academia and in the public domain. Questions concerning what interventions are possible and appropriate with the increasing amount of genetic information available, challenge our understandings of ourselves, our health and wellbeing, and the role of medical ethics, public health, surveillance and risk. However there has been little reflection on the socio-political effects of this new genetic knowledge and the changes in practice that are currently impacting on our lives. Containing contributions from key international researchers, this book examines the broader issues of genetic debates and looks at how prediction and risk assessment is being changed in the arenas of health, medicine and reproduction, bringing new insight on the dangers of surveillance, regulation and increased inequality. Developed out of the Taylor and Francis journal Critical Public Health, the book considers the implications of developments in genetics for contemporary liberal governance, as well as for the future of healthcare and public health.

Principles and Practice of Movement Disorders E-Book

Author: Stanley Fahn,Joseph Jankovic,Mark Hallett

Publisher: Elsevier Health Sciences

ISBN: 1437737706

Category: Medical

Page: 556

View: 530

Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.

Axioms and Principles of Plant Construction

Proceedings of a symposium held at the International Botanical Congress, Sydney, Australia, August 1981

Author: R. Sattler

Publisher: Springer Science & Business Media

ISBN: 9400976364

Category: Philosophy

Page: 186

View: 1580

This volume presents the proceedings of a symposium which I organised for the Developmental Section of the Xlllth International Botanical Congress at Sydney, Australia on August 26, 1981. The paper by Professor T. Sachs, which was received too late for inclusion into the symposium at Sydney, was added to these proceedings because of its direct relevancy and importance. The aim of the symposium was to state in an explicit and comprehensive fashion the most basic axioms and principles of plant morphology and morphogenesis. An awareness of these axioms and principles is of paramount importance since they form. the foundations as well as the goal of structural developmental botany. Both teaching and research are predicated on them. The Introduction by the editor briefly examines the meaning of the concepts "axiom", "principle", and "plant construction". The comprehensive paper by Dr. G. Cusset, a unique historical overview, explicates 37 principles of 5 major conceptual systems and many subsystems. The extensive analysis includes a genealogy of ideas and ways of thinking of major authors ranging from philosophers and naturalists of antiquity to recent investigators of plant form and structure. The bibliography of Dr. Cusset I s paper comprises ca. 700 references. The contribution by Professor H. Mohr focusses on modern principles of morphogenesis and provides a penetrating analysis of scientific explanation in developmental biology. The universal principles (laws) described in this paper apply to all living systems, whereas the more specific principles are limited to plants or only higher plants. Professor T.

Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice E-Book

Author: Michael F Greene,Robert K. Creasy,Robert Resnik,Jay D. Iams,Charles J. Lockwood,Thomas Moore

Publisher: Elsevier Health Sciences

ISBN: 1437721354

Category: Medical

Page: 1300

View: 434

In your practice, you require advanced knowledge of the obstetrical, medical, genetic and surgical complications of pregnancy and their effects on the mother and fetus. With both basic science and clinical information, six new chapters, and an updated color design, you need look no further than the 6th edition of this long-time best seller. Includes both basic science and clinical information to give you comprehensive knowledge of the biology of pregnancy. Acts as an excellent resource for OB/GYNs studying for their Maternal-Fetal Medicine boards — and for practitioners who need quick access to practical information. Provides an updated and focused reference list to keep you up to date on the standards of care in maternal-fetal medicine today. Keeps you current with a new section: Disorders at the Maternal-Fetal Interface...and 6 new chapters: Biology of Parturition, Developmental Origins of Health and Disease, Intrapartum Assessment of Fetal Health, Pathogenesis of Pre-term Birth, Maternal and Fetal Infectious Disorders, and Benign Gynecological Conditions of Pregnancy. Features over 50% new authorship with increased focus on international perspectives. Includes the following hot topics in Maternal-Fetal Medicine: o Biology of Parturition o Fetal Growth o Prenatal Genetic Screening and Diagnosis o Fetal Cardiac Malformations and Arrhythmias o Thyroid Disease and Pregnancy o Management of Depression and Psychoses during Pregnancy and the Puerperium Focuses on evidence based medicine, the current best practice in MFM for diagnosing and treating high risk pregnancies. Includes new illustrations and an updated, color design.

Principles and Practice of Child Psychiatry

Author: Stella Chess,Mahin Hassibi

Publisher: Springer Science & Business Media

ISBN: 146132145X

Category: Medical

Page: 550

View: 8910

Stella Chess's many admirers throughout the world have long looked forward to the day when she would produce her own textbook of child psychiatry. They will not be disappointed in this thoughtful and per ceptive account of the principles and practices of the subject, written in collaboration with Dr. Hassibi. It has all the hallmarks we have come to recognize as distinctive of the Chess approach to child psychiatry-gentle yet subtle and penetrating, always appreciative of the feelings and concerns of both the children and their parents, well informed and critically aware of research findings but far from over awed by the contributions of science, and above all immensely practi cal. Anyone who wants to know how one of the world's outstanding clinicians appraises what child psychiatry has to offer could do no bet ter than to read this book. Child psychiatry differs from general psychiatry in being con cerned with a developing organism, and it is entirely appropriate that the book begins with an account of child development and of the prin cipal theories put forward to explain it. Chess and Hassibi recognize the importance of theory in organizing ideas and in suggesting expla nations, but they remain skeptical of how far existing theories do in fact account for the outstanding issues in development. They note the limitations of all theories in explaining how development takes place and why individual differences occur in the way they do.

Medical Principles and Practice

International Journal of the Kuwait University, Health Science Centre

Author: N.A

Publisher: N.A

ISBN: N.A

Category: Clinical medicine

Page: N.A

View: 984

Pediatric Allergy: Principles and Practice E-Book

Author: Donald Y. M. Leung,Hugh Sampson,Raif Geha,Stanley J. Szefler

Publisher: Elsevier Health Sciences

ISBN: 1437737781

Category: Medical

Page: 704

View: 5300

Pediatric Allergy supplies the comprehensive guidance you need to diagnose, manage, and treat virtually any type of allergy seen in children. Drs. Leung, Sampson, Geha, and Szefler present the new full-color second edition, with coverage of the diagnosis and management of anaphylaxis, the immune mechanisms underlying allergic disease, the latest diagnostic tests, and more. Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians. Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches. Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases. Apply the newest diagnostic tests available—for asthma, upper respiratory allergy, and more—and know their benefits and contraindications. Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases. Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals. Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease. Effectively control asthma and monitor its progression using the new step-by-step approach. Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.

Handbook of Laboratory Animal Science, Volume I, Third Edition

Essential Principles and Practices

Author: Jann Hau,Steven J. Schapiro

Publisher: CRC Press

ISBN: 9781420084566

Category: Medical

Page: 740

View: 5064

Laboratory animal testing provides most of our current knowledge of human physiology, microbiology, immunology, pharmacology, and pathology. From studies of genetics in fruit flies to studies of cellular processes in genetically modified mice to recent dramatic developments in genetics, translational research, and personalized medicines, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences and all rely on access to high-quality laboratory animals as models for humans. Rooted in the principle that good science can only be performed in environments that promote good animal welfare, this third edition of the bestselling Handbook of Laboratory Animal Science, Vol. 1, Essential Principles and Practices emphasizes the importance of implementing the three R’s: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort, and integrates these humane principles into almost every chapter. See what's new in the Third Edition: New chapters: Applications of Radio-Telemetry in Small Laboratory Animals, Generation and analysis of genetically modified mice, and Physiological, Hematological, and Clinical Chemistry Parameters Additional mateiral on the international harmonization of practices and on the continued implementation of the refinement, reduction, and replacement of animal usage in laboratories Sixteen page color insert Relevant to virtually all areas of laboratory science and forming the cornerstone of laboratory animal science, each individual chapter focuses on an important subdiscipline of laboratory animal science including humane laws and guidelines; non-surgical, surgical, microsurgical, and post-mortem procedures; genetic modification; nutrition, feeding, and environmental factors; experiment design and alternative methods; and analgesia, anesthesia, and euthanasia. Each chapter can be read in series or as a stand alone text. A truly international effort from world renowned contributors, Handbook of Laboratory Animal Science, Vol. 1, Essential Principles and Practices, Third Edition is useful as a textbook in laboratory animal science courses for postgraduate and undergraduate students, as a handbook for scientists who work with animals in their research, and for university veterinarians, regulators, and other specialists in laboratory animal science.