Industrial Scale Natural Products Extraction

Author: Hans-Jörg Bart,Stephan Pilz

Publisher: John Wiley & Sons

ISBN: 3527635130

Category: Technology & Engineering

Page: 314

View: 1834

Covering the latest technologies in process engineering, this handbook and ready reference features high pressure processing, alternative solvents and processes, extraction technologies and biotransformations -- describing greener, more efficient and sustainable techniques. The result is an expert account of engineering details from lab-scale experiments to large-scale industrial design. The major focus is on the engineering aspects of extraction with organic and supercritical solvents, ionic liquids or surfactant solutions, and is supplemented by aspects of both up- and downstream processing, biotransformation, as well as a survey of typical products in food, pharmaceutical and cosmetic applications. This is rounded off by market developments, economic considerations and regulations requirements in the field Authored by experts from leading industrial and academic institutions, this is essential reading for the hands-on scientist and office manager alike.

Natural Product Extraction

Principles and Applications

Author: Mauricio A Rostagno,Juliana M Prado

Publisher: Royal Society of Chemistry

ISBN: 1782626220

Category: Science

Page: N.A

View: 3283

Natural products are sought after by the food, pharmaceutical and cosmetics industries, and research continues into their potential for new applications. Extraction of natural products in an economic and environmentally-friendly way is of high importance to all industries involved. This book presents a holistic and in-depth view of the techniques available for extracting natural products, with modern and more environmentally-benign methods, such as ultrasound and supercritical fluids discussed alongside conventional methods. Examples and case studies are presented, along with the decision-making process needed to determine the most appropriate method. Where appropriate, scale-up and process integration is discussed. Relevant to researchers in academia and industry, and students aiming for either career path, Natural Product Extraction presents a handy digest of the current trends and latest developments in the field with concepts of Green Chemistry in mind.

Alternative Solvents for Natural Products Extraction

Author: Farid Chemat,Maryline Abert Vian

Publisher: Springer

ISBN: 3662436280

Category: Science

Page: 315

View: 1803

This book presents a complete picture of the current state-of-the-art in alternative and green solvents used for laboratory and industrial natural product extraction in terms of the latest innovations, original methods and safe products. It provides the necessary theoretical background and details on extraction, techniques, mechanisms, protocols, industrial applications, safety precautions and environmental impacts. This book is aimed at professionals from industry, academicians engaged in extraction engineering or natural product chemistry research, and graduate level students. The individual chapters complement one another, were written by respected international researchers and recognized professionals from the industry, and address the latest efforts in the field. It is also the first sourcebook to focus on the rapid developments in this field.

Green Extraction of Natural Products

Theory and Practice

Author: Farid Chemat,Jochen Strube

Publisher: John Wiley & Sons

ISBN: 3527676813

Category: Science

Page: 300

View: 1626

Extraction processes are essential steps in numerous industrial applications from perfume over pharmaceutical to fine chemical industry. Nowadays, there are three key aspects in industrial extraction processes: economy and quality, as well as environmental considerations. This book presents a complete picture of current knowledge on green extraction in terms of innovative processes, original methods, alternative solvents and safe products, and provides the necessary theoretical background as well as industrial application examples and environmental impacts. Each chapter is written by experts in the field and the strong focus on green chemistry throughout the book makes this book a unique reference source. This book is intended to be a first step towards a future cooperation in a new extraction of natural products, built to improve both fundamental and green parameters of the techniques and to increase the amount of extracts obtained from renewable resources with a minimum consumption of energy and solvents, and the maximum safety for operators and the environment.

Natural Extracts Using Supercritical Carbon Dioxide

Author: Mamata Mukhopadhyay

Publisher: CRC Press

ISBN: 9781420041699

Category: Technology & Engineering

Page: 360

View: 9529

Synthesizing research from a wide variety of sources, this work offers a convenient guide to a clean, safe, inexpensive, non-toxic, non-polluting solvent that performs better than most conventional solvents. Natural Extracts Using Supercritical Carbon Dioxide reviews recent development in the technology and its applications to the food, flavor, fragrance, and pharmaceutical industries. It outlines the many advantages the method has over traditional methods like steam distillation, solvent extraction, and molecular distillation and it supports the popular trend toward the use of natural products in these industries.

Water Extraction of Bioactive Compounds

From Plants to Drug Development

Author: Herminia Dominguez,Maria Jesus Gonzalez Munoz

Publisher: Elsevier

ISBN: 0128096152

Category: Science

Page: 530

View: 3782

Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to drug developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this. Particularly promising are aqueous based methods, as water is a cheap, safe and abundant solvent. The book is a detailed guide to the fundamental concepts and necessary equipment needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Part 1 begins with a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals, the need for standardization and a move toward more rational and greener techniques in the field, the development of plant-based extraction processes and pretreatments for the efficient extraction. Part 2 then reviews a broad range of available techniques, including sections on conventional hot water extraction and pressurized hot water extraction in a range of settings. Intensified processes are then discussed in detail, including sections on microwave-assisted processes, ultrasound-assisted processes and enzyme assisted extraction. Covers the theoretical background and range of techniques available to researchers, helping them to select the most appropriate extraction method for their needs Presents up-to-date and cutting edge applications by international experts Highlights current use and future potential for industrial scale applications Offers a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals

Natural Products Isolation

Author: Satyajit D. Sarker,Zahid Latif,Alexander I. Gray

Publisher: Springer Science & Business Media

ISBN: 1592599559

Category: Science

Page: 515

View: 4057

Natural Products Isolation: Second Edition presents a practical overview of just how natural products can be extracted, prepared, and isolated from the source material. Maintaining the main theme and philosophy of the first edition, this second edition incorporates all the new significant developments in this field of research. The chapters are divided into four distinct sections: introduction, extraction, chromatography, and special topics. This second edition provides substantial backround information for natural product researchers and will prove a useful reference guide to all of the available techniques.

Green Extraction of Natural Products

Theory and Practice

Author: Farid Chemat,Jochen Strube

Publisher: John Wiley & Sons

ISBN: 3527676791

Category: Science

Page: 300

View: 1341

Extraction processes are essential steps in numerous industrial applications from perfume over pharmaceutical to fine chemical industry. Nowadays, there are three key aspects in industrial extraction processes: economy and quality, as well as environmental considerations. This book presents a complete picture of current knowledge on green extraction in terms of innovative processes, original methods, alternative solvents and safe products, and provides the necessary theoretical background as well as industrial application examples and environmental impacts. Each chapter is written by experts in the field and the strong focus on green chemistry throughout the book makes this book a unique reference source. This book is intended to be a first step towards a future cooperation in a new extraction of natural products, built to improve both fundamental and green parameters of the techniques and to increase the amount of extracts obtained from renewable resources with a minimum consumption of energy and solvents, and the maximum safety for operators and the environment.

Natural Products Isolation

Author: Richard J. P. Cannell

Publisher: Springer Science & Business Media

ISBN: 0896033627

Category: Science

Page: 473

View: 2805

Natural Products Isolation provides a comprehensive introduction to techniques for the extraction and purification of natural products from all biological sources. Geared to scientists with little experience of natural products extraction, but offering even skilled researchers valuable advice and insight, Natural Products Isolation lays the foundation for the potential extractor to isolate natural substances efficiently. Its methods and guidance will almost certainly play a major role in today's natural product discovery and development.

Natural Product Extraction

Principles and Applications

Author: Mauricio A Rostagno,Juliana M Prado

Publisher: Royal Society of Chemistry

ISBN: 1782626220

Category: Science

Page: N.A

View: 6586

Natural products are sought after by the food, pharmaceutical and cosmetics industries, and research continues into their potential for new applications. Extraction of natural products in an economic and environmentally-friendly way is of high importance to all industries involved. This book presents a holistic and in-depth view of the techniques available for extracting natural products, with modern and more environmentally-benign methods, such as ultrasound and supercritical fluids discussed alongside conventional methods. Examples and case studies are presented, along with the decision-making process needed to determine the most appropriate method. Where appropriate, scale-up and process integration is discussed. Relevant to researchers in academia and industry, and students aiming for either career path, Natural Product Extraction presents a handy digest of the current trends and latest developments in the field with concepts of Green Chemistry in mind.

Microwave-assisted Extraction for Bioactive Compounds

Theory and Practice

Author: Farid Chemat,Giancarlo Cravotto

Publisher: Springer Science & Business Media

ISBN: 1461448301

Category: Technology & Engineering

Page: 240

View: 6822

With increasing energy prices and the drive to reduce CO2 emissions, food industries are challenged to find new technologies in order to reduce energy consumption, to meet legal requirements on emissions, product/process safety and control, and for cost reduction and increased quality as well as functionality. Extraction is one of the promising innovation themes that could contribute to sustainable growth in the chemical and food industries. For example, existing extraction technologies have considerable technological and scientific bottlenecks to overcome, such as often requiring up to 50% of investments in a new plant and more than 70% of total process energy used in food, fine chemicals and pharmaceutical industries. These shortcomings have led to the consideration of the use of new "green" techniques in extraction, which typically use less solvent and energy, such as microwave extraction. Extraction under extreme or non-classical conditions is currently a dynamically developing area in applied research and industry. Using microwaves, extraction and distillation can now be completed in minutes instead of hours with high reproducibility, reducing the consumption of solvent, simplifying manipulation and work-up, giving higher purity of the final product, eliminating post-treatment of waste water and consuming only a fraction of the energy normally needed for a conventional extraction method. Several classes of compounds such as essential oils, aromas, anti-oxidants, pigments, colours, fats and oils, carbohydrates, and other bioactive compounds have been extracted efficiently from a variety of matrices (mainly animal tissues, food, and plant materials). The advantages of using microwave energy, which is a non-contact heat source, includes more effective heating, faster energy transfer, reduced thermal gradients, selective heating, reduced equipment size, faster response to process heating control, faster start-up, increased production, and elimination of process steps. This book will present a complete picture of the current knowledge on microwave-assisted extraction (MAE) of bioactive compounds from food and natural products. It will provide the necessary theoretical background and details about extraction by microwaves, including information on the technique, the mechanism, protocols, industrial applications, safety precautions, and environmental impacts.

Modern Extraction Techniques

Food and Agricultural Samples

Author: Charlotta Turner,American Chemical Society. Division of Agricultural and Food Chemistry

Publisher: Amer Chemical Society

ISBN: 9780841239401

Category: Science

Page: 189

View: 9510

During the last ten years, several new extraction techniques have been developed that are faster, more automated and use less organic solvents compared to classical solvent extraction techniques. Furthermore, there is a clear trend going towards the use of (and research on) environmentally sustainable methods, which is encouraging for the future. Supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) are two of the most useful techniques for extraction of non-polar and medium polar solutes from solid and semi-solid samples. These techniques commonly use pressurized carbon dioxide or hot liquids such as water as extraction solvents, respectively. For aqueous samples, stir-bar sorptive extraction (SBSE) has recently been developed. These are some of the techniques that will be described in the proposed symposium series book. Focus will be on the extraction of various compounds from food and agricultural samples in either an analytical or a process-scale point-of-view. Several of the book chapters will compare the different techniques, and describe their advantages and disadvantages. Applications discussed in this book include SFE of biopolymers from distillers dried grains, SFE of lipids from oilseeds, PLE of functional ingredients from plants and herbs, tandem SFE/PLE of acrylamide from potato chips, SFE and PLE of cholesterol and fat from hamster liver, and steam distillation-extraction (SDE) and SBSE of flavors from shitake mushrooms.

Natural Products and Drug Discovery

An Integrated Approach

Author: Subhash C. Mandal,Vivekananda Mandal,Tetsuya Konishi

Publisher: Elsevier

ISBN: 0081021046

Category: Science

Page: 776

View: 2123

Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery. Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers. Reviews the changing role of natural products in drug discovery, integrating traditional knowledge with modern molecular technologies Highlights the potential future role of natural products in preventative medicine Supported by real world case studies throughout

Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds

Author: Jose L. Martinez

Publisher: CRC Press

ISBN: 9781420006513

Category: Science

Page: 424

View: 6652

Enhanced concern for the quality and safety of food products, increased preference for natural products, and stricter regulations on the residual level of solvents, all contribute to the growing use of supercritical fluid technology as a primary alternative for the extraction, fractionation, and isolation of active ingredients. As a solvent-free process, supercritical fluid technology is a popular answer for the functional foods and nutraceutical sector, one of the fastest growing consumer driven markets. Recent advancements in the technology and increased utilization of the process demand a comprehensive, single-source review of current and future trends in supercritical fluid technology. Compiling contributions from international experts in the field, Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds presents the state-of-the-science in the extraction and fractionation of bioactive ingredients by supercritical fluids. Focusing on implemented industrial processes and trends, it reviews the fundamentals of the technology and examines the economics of supercritical fluid extraction systems and processes. Over the course of twelve chapters, the book presents the supercritical fluid extraction processes in edible oils, including fish oils and specialty oils; herbs, such as Latin American plants and those used in Traditional Chinese Medicine; algae; spices; antioxidants and essential oils; as well as the processing of micro and nano-scale materials by supercritical fluid technology. Each chapter covers the major active components in the target material, including chemical, physical, nutritional, and pharmaceutical properties; an analysis of the specific supercritical fluid process used; a comparison of traditional processing methods versus supercritical fluid technology; and a set of conclusions with supporting data and insight.

The Application of Green Solvents in Separation Processes

Author: Francisco Pena-Pereira,Marek Tobiszewski

Publisher: Elsevier

ISBN: 0128054433

Category: Science

Page: 560

View: 6245

The Application of Green Solvents in Separation Processes features a logical progression of a wide range of topics and methods, beginning with an overview of green solvents, covering everything from water and organic solvents, to ionic liquids, switchable solvents, eutectic mixtures, supercritical fluids, gas-expanded solvents, and more. In addition, the book outlines green extraction techniques, such as green membrane extraction, ultrasound-assisted extraction, and surfactant-mediated extraction techniques. Green sampling and sample preparation techniques are then explored, followed by green analytical separations, including green gas and liquid capillary chromatography, counter current chromatography, supercritical fluid chromatography, capillary electrophoresis, and other electrical separations. Applications of green chemistry techniques that are relevant for a broad range of scientific and technological areas are covered, including the benefits and challenges associated with their application. Provides insights into recent advances in greener extraction and separation processes Gives an understanding of alternatives to harmful solvents commonly used in extraction and separation processes, as well as advanced techniques for such processes Written by a multidisciplinary group of internationally recognized scientists

Handbook of Coffee Processing By-Products

Sustainable Applications

Author: Charis Michel Galanakis

Publisher: Academic Press

ISBN: 0128112913

Category: Technology & Engineering

Page: 426

View: 1506

Handbook of Coffee Processing By-Products: Sustainable Applications presents alternative and sustainable solutions for coffee processing by-products and specifies their industrial potential, both as a source for the recovery of bioactive compounds and their reutilization in the pharmaceutical, biotechnological, food, biotechnology, and cosmetic industries, also covering environmental and agronomic applications. This book addresses key topics specific to sustainable management in the coffee industry, placing an emphasis on integrated solutions for the valorization and upgrade of coffee processing by-products, biorefinery, and different techniques for the separation, extraction, recovery and formulation of polyphenols. Specifies potential for the use of by-products as a source for the recovery of bioactive compounds and their reutilization in the pharmaceutical, biotechnological, food, biotechnology and cosmetic industries Places emphasis on integrated solutions for the valorization and upgrade of coffee processing by-products, biorefinery, and different techniques for the separation, extraction, recovery and formulation of polyphenols

Handbook of Grape Processing By-Products

Sustainable Solutions

Author: Charis Michel Galanakis

Publisher: Academic Press

ISBN: 0128098716

Category: Science

Page: 326

View: 6902

Handbook of Grape Processing By-Products explores the alternatives of upgrading production by-products, also denoting their industrial potential, commercial applications and sustainable solutions in the field of grape valorization and sustainable management in the wine industry. Covering the 12 top trending topics of winery sustainable management, emphasis is given to the current advisable practices in the field, general valorization techniques of grape processing by-products (e.g. vermi-composting, pyrolysis, re-utilization for agricultural purposes etc.), the newly introduced biorefinery concept, different techniques for the separation, extraction, recovery and formulation of polyphenols, and finally, the healthy components of grape by-products that lead to target applications in the pharmaceutical, enological, food and cosmetic sectors. Presents in-depth information on grape processing Addresses the urgent need for sustainability within wineries Reveals the opportunities of reutilizing processing by-products in profitable ways Explores general valorization methods and separation and extraction methods for the recovery of high added-value extracts/compounds and their transformation to final products

Separation, Extraction and Concentration Processes in the Food, Beverage and Nutraceutical Industries

Author: Syed S. H. Rizvi

Publisher: Elsevier

ISBN: 0857090755

Category: Technology & Engineering

Page: 694

View: 5560

Separation, extraction and concentration are essential processes in the preparation of key food ingredients. They play a vital role in the quality optimization of common foods and beverages and there is also increasing interest in their use for the production of high-value compounds, such as bioactive peptides from milk and whey, and the recovery of co-products from food processing wastes. Part one describes the latest advances in separation, extraction and concentration techniques, including supercritical fluid extraction, process chromatography and membrane technologies. It also reviews emerging techniques of particular interest, such as pervaporation and pressurised liquid extraction. Part two then focuses on advances in separation technologies and their applications in various sectors of the food, beverage and nutraceutical industries. Areas covered include dairy and egg processing, oilseed extraction, and brewing. This section discusses the characteristics of different foods and fluids, how food constituents are affected by separation processes and how separation processes can be designed and operated to optimize end product quality. With its team of experienced international contributors, Separation, extraction and concentration processes in the food, beverage and nutraceutical industries is an important reference source for professionals concerned with the development and optimisation of these processes. Describes the latest advances in separation, extraction and concentration techniques and their applications in various sectors of the food, beverage and nutraceutical industries Reviews emerging techniques of particular interest, such as pervaporation and pressurised liquid extraction Explores the characteristics of different foods and fluids and how food constituents are affected by separation processes

Soft Chemistry and Food Fermentation

Author: Alexandru Mihai Grumezescu,Alina Maria Holban

Publisher: Academic Press

ISBN: 0128112042

Category: Technology & Engineering

Page: 548

View: 7464

Soft Chemistry and Food Fermentation, Volume Three, the latest release in the Handbook of Food Bioengineering series is a practical resource that provides significant knowledge and new perspectives in food processing and preservation, promoting renewable resources by applying soft ecological techniques (i.e. soft chemistry). Fermentation represents a simple and very efficient way to preserve food in developing countries where other methods, depending on specialized instruments, are not available. Through processes of soft chemistry and fermentation, food ingredients can be produced with improved properties (such as pharmabiotics) able to promote health. Includes the most recent scientific progress with proven biological, physical and chemical applications of the food engineering process to understand fermentation Presents novel opportunities and ideas for developing and improving technologies in the food industry that are useful to researchers in food bioengineering Provides eco-friendly approaches towards components, materials and technologies developed for improvements in food quality and stability Includes valuable information useful to a wide audience interested in food chemistry and the bioremediation of new foods

Bioactive Natural Products

Opportunities and Challenges in Medicinal Chemistry

Author: Goutam Brahmachari

Publisher: World Scientific

ISBN: 9814335371

Category: Science

Page: 670

View: 2744

Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.