A Guide Through Experiments
Author: Nicolas Bogliotti,Roba Moumné
Publisher: John Wiley & Sons
Combining theoretical knowledge of synthetic transformations, practical considerations, structural elucidation by interpretation of spectroscopic data as well as rationalization of structure-property relations, this textbook presents a series of 16 independent exercises, including detailed descriptions of experimental procedures, questions, and answers. The experimental descriptions are very helpful for guiding less experienced students towards a better understanding of practical aspects in synthetic organic chemistry, while the broad scope of the questions and answers is excellent for learning purposes. The exercises are based on published research articles, adapted for didactic purposes, and will thus inspire students by way of having to solve real-life problems in chemistry. A must-have for MSc and PhD students as well as postdocs in organic chemistry and related disciplines, and lecturers and organizers of lab courses in organic chemistry.
Author: Joaquín Isac-García,José A. Dobado,Francisco G. Calvo-Flores,Henar Martínez-García
Publisher: Academic Press
Experimental Organic Chemistry: Laboratory Manual is designed as a primer to initiate students in Organic Chemistry laboratory work. Organic Chemistry is an eminently experimental science that is based on a well-established theoretical framework where the basic aspects are well established but at the same time are under constant development. Therefore, it is essential for future professionals to develop a strong background in the laboratory as soon as possible, forming good habits from the outset and developing the necessary skills to address the challenges of the experimental work. This book is divided into three parts. In the first, safety issues in laboratories are addressed, offering tips for keeping laboratory notebooks. In the second, the material, the main basic laboratory procedures, preparation of samples for different spectroscopic techniques, Microscale, Green Chemistry, and qualitative organic analysis are described. The third part consists of a collection of 84 experiments, divided into 5 modules and arranged according to complexity. The last two chapters are devoted to the practices at Microscale Synthesis and Green Chemistry, seeking alternatives to traditional Organic Chemistry. Organizes lab course coverage in a logical and useful way Features a valuable chapter on Green Chemistry Experiments Includes 84 experiments arranged according to increasing complexity
Author: John C. Gilbert,Stephen F. Martin
Publisher: Cengage Learning
Perform chemistry experiments with skill and confidence in your organic chemistry lab course with this easy-to-understand lab manual. EXPERIMENTAL ORGANIC CHEMISTRY: A MINISCALE AND MICROSCALE APPROACH, Sixth Edition first covers equipment, record keeping, and safety in the laboratory, then walks you step by step through the laboratory techniques you'll need to perform all experiments. Individual chapters show you how to use the techniques to synthesize compounds and analyze their properties, complete multi-step syntheses of organic compounds, and solve structures of unknown compounds. New experiments in Chapter 17 and 18 demonstrate the potential of chiral agents in fostering enantioselectivity and of performing solvent-free reactions. A bioorganic experiment in Chapter 24 gives you an opportunity to accomplish a mechanistically interesting and synthetically important coupling of two a-amino acids to produce a dipeptide. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Author: Stanley Sandler
Polymer Syntheses, Volume II presents detailed laboratory instructions for the preparation of different types of polymers. This book provides information pertinent to useful polymer synthesis. Organized into 10 chapters, this volume begins with an overview of resins derived from urea, melamine, or benzoguanamine. This text then examines the reaction of formaldehyde with hydrogen chloride, which has been shown to lead to the spontaneous production of carcinogen bis(chloromethyl) ether. Other chapters consider the topic of silicone resins or polyorganosiloxanes, as well as the uses of vinyl ether polymers in lacquer resins, adhesives, plasticizers, paints, and copolymer compositions. This book discusses as well the methods of polymerization of acrylic and of methacrylic acid. The final chapter deals with the health and safety aspects of the production of the monomer vinyl chloride. This book is a valuable resource for industrial and polymer chemists. Students of polymer chemistry will also find this book useful.
Organic Synthesis using Reaxys and SciFinder
Author: Michael B. Smith,John D'Angelo
Designed to supplement existing organic textbooks, Hybrid Retrosynthesis presents a relatively simple approach to solving synthesis problems, using a small library of basic reactions along with the computer searching capabilities of Reaxys and SciFinder. This clear, concise guide reviews the essential skills needed for organic synthesis and retrosynthesis, expanding reader knowledge of the foundational principles of these techniques, whilst supporting their use via practical methodologies. Perfect for both graduate and post-graduate students, Hybrid Retrosynthesis provides new applied skills and tools to help during their organic synthesis courses and future careers, whilst simultaneously acting as useful resource for those setting tutorial and group problems, and as a helpful go-to guide for organic chemists involved in either industry or academia. Ideal revision and hands on learning guide for organic synthesis Clearly explains the principles and practice of retrosynthesis, which is often not covered in other books Encourages readers to practice their synthetic knowledge supported by real life examples
with multistep and multiscale syntheses : instructor's manual
Author: Dana W. Mayo
Author: Louis Frederick Fieser,Kenneth L. Williamson
Publisher: Houghton Mifflin
Category: Chemistry, Organic
The Learner's Approach
Author: Kim Seng Chan,Jeanne Tan
Publisher: World Scientific Publishing Company
This book is a continuation of authors' previous six books — Understanding Advanced Physical Inorganic Chemistry, Understanding Advanced Organic and Analytical Chemistry, Understanding Advanced Chemistry Through Problem Solving Vol. I & II, Understanding Basic Chemistry and Understanding Basic Chemistry Through Problem Solving, retaining the main refutational characteristics of the previous books with the strategic inclusion of think-aloud questions to promote conceptual understanding during an experimental planning. These essential questions would make learners aware of the rationale behind each procedural step, the amount of chemical used and types of apparatus that are appropriate for the experiment. The book provides a fundamental important scaffolding to aid students to create their own understanding of how to plan an experiment based on the given reagent and apparatus. It guides the students in integrating the various concepts that they have learnt into a coherent and meaningful conceptual network during experimental planning. Existing A-level or IB guidebooks generally introduce concepts in a matter-of-fact manner. This book adds a unique pedagogical edge which few can rival. This book is essential and useful in order for students to be adequately prepared for their high stake examinations.
Author: Roger S. Macomber
Publisher: University Science Books
The second of a two-volume set designed for a course focused on the fundamentals of organic chemistry for pre-meds, and chemistry/bioscience students. It describes the chemical properties and reactions of the common classes of organic compounds, and multi-step syntheses of complex molecules.
The Dendral Project
Author: Robert K. Lindsay
Publisher: McGraw-Hill Companies
Author: Carlos A. M. Afonso,Nuno R. Candeias,Dulce Pereira Simão,Alexandre F. Trindade,Jaime A. S. Coelho,Bin Tan,Robert Franzén
Publisher: Royal Society of Chemistry
This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.
Methods and Techniques
Author: Richard Monson
Advanced Organic Synthesis: Methods and Techniques presents a survey and systematic introduction to the modern techniques of organic synthesis. The book attempts to acquaint the reader with a variety of laboratory techniques as well as introduce chemical reagents that require deftness and care in handling. Chapters are devoted that discuss the techniques of organic synthesis; apparatus and terminology used in the description of synthetic procedures; the scope and mechanism of chemical reactions; and technical procedures on how to perform chemical experiments. The text will be of vital importance to advanced undergraduate student or beginning graduate student of chemistry.
A Small-scale Approach
Author: Charles F. Wilcox,Mary F. Wilcox
Publisher: Prentice Hall
This text is suitable for second year organic laboratory courses taught in the chemistry department. This thorough introduction to organic laboratory techniques presents an integrated view of the theory underlying technique while aiming to provide an understanding of the techniques rather than mere training in their use. With experiments covering a wide range of scales from micro to standard, this text emphasizes the middle ground, small scale, providing large enough amounts of materials to develop the required manipulative skills while minimizing the costs and hazards of the materials employed.
Strategy and Control
Author: Paul Wyatt,Stuart Warren
Publisher: John Wiley & Sons
Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. A comprehensive, practical account of the key concepts involved in synthesising compounds Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations Focuses on reactions that really work rather than those with limited application Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.
a skeptic's guide to the creation of life on earth
Author: Robert Shapiro
Publisher: Bantam Dell Pub Group
Describes theories, beliefs, and myths concerning the origin of life, discusses the principle features of cellular life, and looks at evolution and its fossil evidence
A Step-by-Step Approach to Understanding Organic Reaction Mechanisms
Author: Timothy K. Dickens,Stuart Warren
Publisher: John Wiley & Sons
Teaches and enables students to build confidence in drawing and manipulating curly arrows, a fundamental skill for all organic chemists This book is an interactive approach to learning about chemistry of the carbonyl group—inviting students to work through its pages with pencil and paper in hand. It educates with the belief that the most effective way to learn is by practice and interaction. With this in mind, the reader is asked to predict what would happen under a specific set of reaction conditions. The book is divided into frames: each frame poses a question and invites the reader to predict what will happen. Subsequent frames give the solution but then pose more questions to develop a theme further. Chemistry of the Carbonyl Group: A Programmed Approach to Organic Reaction Mechanisms, Revised Edition provides a solid grounding in the fundamental reactions of carbonyls. Presented in full colour to enhance the understanding of mechanisms within chemistry, the chapters of this step-by-step guide cover: nucleophilic addition to the carbonyl group; nucleophilic substitution; nucleophilic substitution at the carbonyl group with complete removal of carbonyl oxygen; carbanions and enolisation; and building organic molecules from carbonyl compounds. A must-have book for undergraduate chemists to emphasise understanding in carbonyl group chemistry Goes through all the stages of basic carbonyl chemistry, detailing even the simplest mechanisms A step-by-step learning guide to synthetic chemistry for the first year of a chemistry degree, with all the information needed for independent learning Provides a solid grounding in the fundamental reactions of carbonyls which will inform the understanding of many other organic chemistry reactions Chemistry of the Carbonyl Group: A Programmed Approach to Organic Reaction Mechanisms - Revised Edition is packed with all the information on synthetic chemistry that every first-year student will need in order to learn independently.
Author: John Leonard,Barry Lygo,Garry Procter
Publisher: CRC Press
Any research that uses new organic chemicals, or ones that are not commercially available, will at some time require the synthesis of such compounds. Therefore, organic synthesis is important in many areas of both applied and academic research, from chemistry to biology, biochemistry, and materials science. The third edition of a bestseller, Advanced Practical Organic Chemistry is a guide that explains the basic techniques of organic chemistry, presenting the necessary information for readers to carry out widely used modern organic synthesis reactions. This book is written for advanced undergraduate and graduate students as well as industrial organic chemists, particularly those involved in pharmaceutical, agrochemical, and other areas of fine chemical research. It provides the novice or nonspecialist with the often difficult-to-find information on reagent properties needed to perform general techniques. With over 80 years combined experience training and developing organic research chemists in industry and academia, the authors offer sufficient guidance for researchers to perform reactions under conditions that give the highest chance of success, including the appropriate precautions to take and proper experimental protocols. The text also covers the following topics: Record keeping and equipment Solvent purification and reagent preparation Using gases and working with vacuum pumps Purification, including crystallization and distillation Small-scale and large-scale reactions Characterization, including NMR spectra, melting point and boiling point, and microanalysis Efficient ways to find information in the chemical literature With fully updated text and all newly drawn figures, the third edition provides a powerful tool for building the knowledge on the most up-to-date techniques commonly used in organic synthesis.
A Curriculum Resource
Author: Frank Ellis,Colin Osborne
Publisher: Royal Society of Chemistry
Aimed at post-16 students, this book provides a series of classroom activities, both written and practical, relating to paracetamol.
Author: Pietro Tundo,John Andraos
Publisher: CRC Press
Many new methods directed to organic and inorganic syntheses of useful intermediates are being developed to specifically address green and sustainable chemistry principles. Highlighting the importance of green metrics, the Green Syntheses series focuses on how to reliably substantiate and validate the level of "greenness" of chemical processes, providing practical synthetic methodologies and metrics for a rigorous proof of "greenness." In Green Syntheses, Volume 1, the first book of its kind, the editors determine appropriate material efficiency green metrics and use them to compare syntheses provided by the chapter authors with those previously published. Presenting a new concept in green chemistry, this book demonstrates what future publications might look like if green principles are followed and also incorporate the important ethical aspect of supplying rigorous procedures in laboratory practice and evidence of greenness of a given synthesis protocol using metrics analysis. This inaugural volume initiates the much-needed transition from stating the 12 guiding principles on the philosophy of green chemistry to the actualization and verification of it. The book addresses primarily the issue of material efficiency metrics, which measure the amount of waste produced relative to desired product. In each contributed example, full experimental details are given showing all quantities of materials used in the procedure. Authors discuss the green merits of their protocols in conjunction with the results of a thorough metrics analysis, allowing for in-depth discussion of insights about synthesis strategy and performance characteristics of the new and prior cited plans.
Author: Anthony W. Czarnik,Sheila Hobbs Dewitt
Publisher: Amer Chemical Society
Combinatorial chemistry is the ability to simultaneously synthesize vast numbers of diverse compounds. Its techniques have revolutionized the drug discovery process, and are widely used throughout the biotechnology community. Aimed at a wide audience, this text is a down-to-earth introductionto small molecule combinatorial chemistry. It uses a tutorial approach to provide a detailed survey of solid-phase peptide synthesis and solution-phase synthesis. It also reviews current automated approaches and equipment for both solid- and solution-phase library synthesis.