Pilot Plants and Scale-up of Chemical Processes II

Author: William Hoyle

Publisher: N.A

ISBN: 9780854047192

Category: Science

Page: 120

View: 9732

How do you translate bench chemistry into 10 -100 litre pilot plant scale? Drawing on the wealth of experience of its expert contributors, Pilot Plants and Scale-up of Chemical Processes II provides an insight into how methods, procedures and techniques can be optimised. Up-to-date and highly focused, this book addresses topics including the choice of phase-transfer catalyst, safe scale-up of both Grignard and organolithium reactions, and on-line techniques for examining crystallisation. Newly established collaborative industry/academia projects are discussed, along with other procedures that have a practical application in industry. As a source of innovative techniques and best current practice, this book is a must for process development and pilot plant chemists as well as chemical engineers.

Pilot Plants and Scale-up of Chemical Processes

Author: William Hoyle

Publisher: Royal Society of Chemistry

ISBN: N.A

Category: Science

Page: 97

View: 4060

One of the biggest challenges facing today's chemist and chemical engineer is the translation of bench chemistry to the pilot plant. This book provides expert insights into current best practice, and will prove an indispensable manual for all those involved in pilot plant design and scale-up implementation - process chemists, engineers and managers alike. The international expertise of the contributors covers a wide range of topics, and new material covered includes: the removal of heavy metals from effluent, heat flow calorimetry, low temperature processes, good manufacturing practice in pilot plants, design issues, the use of statistical methods in the running of pilot plants. Pilot Plants and Scale-Up of Chemical Processes is a must for all those who are, and wish to remain, expert in the field, providing for the first time in print, a comprehensive and unique perspective of pilot plant production.

Fluidverfahrenstechnik

Grundlagen, Methodik, Technik, Praxis

Author: Ralf Goedecke

Publisher: John Wiley & Sons

ISBN: 3527332707

Category: Chemical engineering

Page: 1219

View: 7230

Diese umfassendste Darstellung des Themas in deutscher Sprache wurde von namhaften Experten aus Hochschule und Industrie geschrieben. Grundlagen und Praxis der Fluidverfahrenstechnik werden allgemeinverständlich und mit vielen Praxisbeispielen erklärt. Die Studienausgabe enthält den kompletten Inhalt der Erstausgabe: über 1200 Seiten mit Expertenwissen, die keine Fragen offen lassen. Mit seiner breit gefächerten Thematik ist das Buch ein zuverlässiger Begleiter für Planungs- und Betriebsingenieure wie für Neueinsteiger und Hochschulabgänger, die Grundlagenwissen in die Praxis umsetzen wollen. "... zeichnet sich neben der Methodik vor allem auch durch den Praxisbezug und das beschriebene Erfahrungswissen aus. ... Es kann als Wissensvermittler, Ratgeber und auch als Nachschlagewerk empfohlen werden." (Filtrieren und Separieren)

Scale-up

Modellübertragung in der Verfahrenstechnik

Author: Marko Zlokarnik

Publisher: John Wiley & Sons

ISBN: 3527660461

Category: Science

Page: 295

View: 3223

Die Übertagung von Verfahren aus dem Labor-bzw. dem Techni-kumsmaßstab in den industriellen maßstab einer Produktiosanlage ist eine der wichtigsten ingenieurstechnischen Aufgaben in der chemischen Industrie. Die einzige zuverlässige Methode dazu basiert auf der Darstellung von Versuchsergebnissen im zutreffenden dimensions-analytischen Raum, der sich als maßstabsinvariant erweist. Das Buch ist in zwei Teile gegliedert: In der ersten Hälfte werden die vertiefte mathematische Vorkenntnisse dieses Themengebiet näherzubringen. Diskutiert werden die Grundlagen der Dimensionsanalyse, die Behandlung von temperaturabhängigen und von rheologischen Stoffwerten und die Modellübertragung bei Nichtverfügbarkeit von Modellstoffsystemen, sowie bei partieller Ähnlichkeit/ All dies wird dem leser anhand von 20 modernen Beispielen aus der heutigen verfahrenstechnischcen Praxis illustriert, der sich mit 25 in dieser Auflage neu hinzugekommenen Übungsaufgaben sein Verständnis aktive erarbeiten und anhand der Lösungen kontrollieren kann. Im zweitem Teil des Buches werden die einzelnen verfahrenstechnischen Grundoperationen aus den Bereichen mechanische, thermische und chemische Verfahrenstechnik aus der Sicht der Dimensionsanalyse und der Modellübertragung beispielhaft behandelt, und es werden für jede Operation die Maßstabsübertragungsregeln vorgestellt und diskutiert. Das vorliegende Buch wendet sich dementsprechend an Studenten wie auch bereits auf dem gebiet tätige Ingenieure, Chemiker und Verfahrenstechniker.

Kirk-Othmer Encyclopedia of Chemical Technology

Author: Kirk-Othmer

Publisher: Wiley-Interscience

ISBN: 9780471485049

Category: Science

Page: 890

View: 382

The fifth edition of the Kirk-Othmer Encyclopedia of Chemical Technology builds upon the solid foundation of the previous editions, which have proven to be a mainstay for chemists, biochemists, and engineers at academic, industrial, and government institutions since publication of the first edition in 1949. The new edition includes necessary adjustments and modernisation of the content to reflect changes and developments in chemical technology. Presenting a wide scope of articles on chemical substances, properties, manufacturing, and uses; on industrial processes, unit operations in chemical engineering; and on fundamentals and scientific subjects related to the field. The Encyclopedia describes established technology along with cutting edge topics of interest in the wide field of chemical technology, whilst uniquely providing the necessary perspective and insight into pertinent aspects, rather than merely presenting information. * Set began publication in January 2004 * Over 1,000 articles * More than 600 new or updated articles * 27 volumes

The Pilot Plant Real Book

A Unique Handbook for the Chemical Process Industry

Author: Francis X. McConville

Publisher: Fxm Engineering & Design

ISBN: 9780972176910

Category: Chemical plants

Page: 312

View: 3711

Handbook for chemists, chemical engineers, technicians. Information on chemicals, solvents, gases, materials, the selection of reactors, chillers, filters, pumps and other equipment, conversion factors, mathematical formulas, fundamentals of heat transfer, temperature control, safe operation of electrical equipment, chemical hygiene & safety, plus rules of thumb and recommendations for the safe, efficient operation of a small chemical pilot facility.

Scale-up Methodology for Chemical Processes

Author: Jean-Paul Euzen,Pierre Trambouze,Jean-Pierre Wauquier

Publisher: Editions TECHNIP

ISBN: 9782710806462

Category: Technology & Engineering

Page: 240

View: 2258

Having gained considerable experience in process development at the Institut FranCais du PEtrole, the authors present a design framework, a review of the available means of investigation, and several examples illustrating their methodology of industrial process scale up. The salient feature of the book is the fact that it addresses a subject which is vital in view of its economic repercussions, yet relatively unknown in technical and scientific circles, due to the confidentiality surrounding it.Contents: 1. Main guidelines of the methodology. 2. Various types of model. 3. Pilot plants and mock-ups. 4. Experimental techniques. 5. Applications to industrial process development. 6. Conclusions. References. Index.

Mikrosystemtechnik-Kongress 2005

10. bis 12. Oktober 2005 in Freiburg

Author: Roland Zengerle

Publisher: Margret Schneider

ISBN: 3800729261

Category:

Page: 880

View: 1059

Lees' Loss Prevention in the Process Industries

Hazard Identification, Assessment and Control

Author: Sam Mannan

Publisher: Butterworth-Heinemann

ISBN: 0750675551

Category: Business & Economics

Page: 3680

View: 1840

Over the last three decades the process industries have grown very rapidly, with corresponding increases in the quantities of hazardous materials in process, storage or transport. Plants have become larger and are often situated in or close to densely populated areas. Increased hazard of loss of life or property is continually highlighted with incidents such as Flixborough, Bhopal, Chernobyl, Three Mile Island, the Phillips 66 incident, and Piper Alpha to name but a few. The field of Loss Prevention is, and continues to, be of supreme importance to countless companies, municipalities and governments around the world, because of the trend for processing plants to become larger and often be situated in or close to densely populated areas, thus increasing the hazard of loss of life or property. This book is a detailed guidebook to defending against these, and many other, hazards. It could without exaggeration be referred to as the "bible" for the process industries. This is THE standard reference work for chemical and process engineering safety professionals. For years, it has been the most complete collection of information on the theory, practice, design elements, equipment, regulations and laws covering the field of process safety. An entire library of alternative books (and cross-referencing systems) would be needed to replace or improve upon it, but everything of importance to safety professionals, engineers and managers can be found in this all-encompassing reference instead. Frank Lees' world renowned work has been fully revised and expanded by a team of leading chemical and process engineers working under the guidance of one of the world's chief experts in this field. Sam Mannan is professor of chemical engineering at Texas A&M University, and heads the Mary Kay O'Connor Process Safety Center at Texas A&M. He received his MS and Ph.D. in chemical engineering from the University of Oklahoma, and joined the chemical engineering department at Texas A&M University as a professor in 1997. He has over 20 years of experience as an engineer, working both in industry and academia New detail is added to chapters on fire safety, engineering, explosion hazards, analysis and suppression, and new appendices feature more recent disasters. The many thousands of references have been updated along with standards and codes of practice issued by authorities in the US, UK/Europe and internationally. In addition to all this, more regulatory relevance and case studies have been included in this edition. Written in a clear and concise style, Loss Prevention in the Process Industries covers traditional areas of personal safety as well as the more technological aspects and thus provides balanced and in-depth coverage of the whole field of safety and loss prevention. - A must-have standard reference for chemical and process engineering safety professionals - The most complete collection of information on the theory, practice, design elements, equipment and laws that pertain to process safety - Only single work to provide everything; principles, practice, codes, standards, data and references needed by those practicing in the field

Process Understanding

For Scale-Up and Manufacture of Active Ingredients

Author: Ian Houson

Publisher: John Wiley & Sons

ISBN: 3527637168

Category: Science

Page: 370

View: 2949

Process Understanding is the underpinning knowledge that allows the manufacture of chemical entities to be carried out routinely, robustly and to the required standard of quality. This area has gained in importance over the last few years, particularly due to the recent impetus from the USA`s Food and Drug Administration. This book covers the multidisciplinary aspects required for successful process design, safety, modeling, scale-up, PAT, pilot plant implementation, plant design as well the rapidly expanding area of outsourcing. In discussing what process understanding means to different disciplines and sectors throughout a product`s life cycle, this handbook and ready reference reveals the factors important to the development and manufacture of chemicals. The book focuses on the fundamental scientific understanding necessary. for a smoother technical transfer between the disciplines, leading to more effective and effi cient process development and manufacturing. A range of case studies are used to exemplify and illustrate the main issues raised. As a result, readers will appreciate that process understanding can deliver a real competitive advantage within the pharmaceuticals and fine chemicals industry. This book serves as an aid to meeting the stringent regulations required by the relevant authorities through demonstrable understanding of the underlying science.

Modeling of Chemical Kinetics and Reactor Design

Author: A. Kayode Coker

Publisher: Elsevier

ISBN: 0080491901

Category: Technology & Engineering

Page: 1136

View: 4926

Selecting the best type of reactor for any particular chemical reaction, taking into consideration safety, hazard analysis, scale-up, and many other factors is essential to any industrial problem. An understanding of chemical reaction kinetics and the design of chemical reactors is key to the success of the of the chemist and the chemical engineer in such an endeavor. This valuable reference volume conveys a basic understanding of chemical reactor design methodologies, incorporating control, hazard analysis, and other topics not covered in similar texts. In addition to covering fluid mixing, the treatment of wastewater, and chemical reactor modeling, the author includes sections on safety in chemical reaction and scale-up, two topics that are often neglected or overlooked. As a real-world introduction to the modeling of chemical kinetics and reactor design, the author includes a case study on ammonia synthesis that is integrated throughout the text. The text also features an accompanying CD, which contains computer programs developed to solve modeling problems using numerical methods. Students, chemists, technologists, and chemical engineers will all benefit from this comprehensive volume. Shows readers how to select the best reactor design, hazard analysis, and safety in design methodology Features computer programs developed to solve modeling problems using numerical methods

Upstream Industrial Biotechnology, 2 Volume Set

Author: Michael C. Flickinger

Publisher: John Wiley & Sons

ISBN: 1118619277

Category: Science

Page: 1854

View: 1699

Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all,) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource.

Industrial Process Scale-up

A Practical Innovation Guide from Idea to Commercial Implementation

Author: Jan Harmsen

Publisher: Elsevier

ISBN: 0444627391

Category: Technology & Engineering

Page: 112

View: 4829

This book will help industrial process innovators in research, development and commercial start-up to assess the risks of commercial-scale implementation and provide them with practical guidelines and methods to reduce the risks to acceptable levels. The book can also be used in co-operation with industrial R&D people and academic researchers to shape open innovation programs and in education as a reference book for process innovation courses. Offers easily accessible, step-by-step, and concise guidelines for industrial process scale-up Explains each stage of the innovation funnel: research, development, demonstration, commercial implementation for any process type and branch Based on industrial experiences and practices, which reduces the risks of commercial scale implementation of new processes to acceptable levels and reduces cost and time of process innovation Very clear, attractive layout, using text boxes that contain clarifying notes and additional information on specific topics, which makes it a quick reference of main subjects and additional information

Chemical Process Equipment - Selection and Design (Revised 2nd Edition)

Author: James R. Couper,W. Roy Penney,James R. Fair, PhD

Publisher: Gulf Professional Publishing

ISBN: 9780080919720

Category: Technology & Engineering

Page: 832

View: 6775

A facility is only as efficient and profitable as the equipment that is in it: this highly influential book is a powerful resource for chemical, process, or plant engineers who need to select, design or configures plant sucessfully and profitably. It includes updated information on design methods for all standard equipment, with an emphasis on real-world process design and performance. The comprehensive and influential guide to the selection and design of a wide range of chemical process equipment, used by engineers globally • Copious examples of successful applications, with supporting schematics and data to illustrate the functioning and performance of equipment Revised edition, new material includes updated equipment cost data, liquid-solid and solid systems, and the latest information on membrane separation technology Provides equipment rating forms and manufacturers’ data, worked examples, valuable shortcut methods, rules of thumb, and equipment rating forms to demonstrate and support the design process Heavily illustrated with many line drawings and schematics to aid understanding, graphs and tables to illustrate performance data

Fundamentals of Food Biotechnology

Author: Byong H. Lee

Publisher: John Wiley & Sons

ISBN: 1118384911

Category: Science

Page: 544

View: 3826

Food biotechnology is the application of modern biotechnologicaltechniques to the manufacture and processing of food, for examplethrough fermentation of food (which is the oldest biotechnologicalprocess) and food additives, as well as plant and animal cellcultures. New developments in fermentation and enzyme technologicalprocesses, molecular thermodynamics, genetic engineering, proteinengineering, metabolic engineering, bioengineering, and processesinvolving monoclonal antibodies, nanobiotechnology and quorumsensing have introduced exciting new dimensions to foodbiotechnology, a burgeoning field that transcends many scientificdisciplines. Fundamentals of Food Biotechnology, 2nd edition is basedon the author’s 25 years of experience teaching on a foodbiotechnology course at McGill University in Canada. The book willappeal to professional food scientists as well as graduate andadvanced undergraduate students by addressing the latest excitingfood biotechnology research in areas such as genetically modifiedfoods (GMOs), bioenergy, bioplastics, functionalfoods/nutraceuticals, nanobiotechnology, quorum sensing andquenching. In addition, cloning techniques for bacterial and yeastenzymes are included in a “New Trends and Tools”section and selected references, questions and answers appear atthe end of each chapter. This new edition has been comprehensively rewritten andrestructured to reflect the new technologies, products and trendsthat have emerged since the original book. Many new aspectshighlight the short and longer term commercial potential of foodbiotechnology.

Design of Multiphase Reactors

Author: Vishwas G. Pangarkar

Publisher: John Wiley & Sons

ISBN: 1118807766

Category: Technology & Engineering

Page: 536

View: 1620

Details simple design methods for multiphase reactors in the chemical process industries Includes basic aspects of transport in multiphase reactors and the importance of relatively reliable and simple procedures for predicting mass transfer parameters Details of design and scale up aspects of several important types of multiphase reactors Examples illustrated through design methodologies presenting different reactors for reactions that are industrially important Includes simple spreadsheet packages rather than complex algorithms / programs or computational aid

Fine Chemicals Manufacture

Technology and Engineering

Author: Andrzej Cybulski,J. A. Moulijn,M. M. Sharma,R. A. Sheldon

Publisher: Gulf Professional Publishing

ISBN: 9780444822024

Category: Technology & Engineering

Page: 551

View: 3456

The sector of fine chemicals, including pharmaceuticals, agrochemicals, dyes and pigments, fragrances and flavours, intermediates, and performance chemicals is growing fast. For obvious reasons chemistry is a key to the success in developing new processes for fine chemicals. However, as a rule, chemists formulate results of their work as recipes, which usually lack important information for process development. Fine Chemicals Manufacture, Technology and Engineering is intended to show what is needed to make the recipe more useful for process development purposes and to transform the recipe into an industrial process that will be safe, environmentally friendly, and profitable. The goal of this book is to form a bridge between chemists and specialists of all other branches involved in the scale-up of new processes or modification of existing processes with both a minimum effort and risk and maximum profit when commercializing the process. New techniques for scale-up and optimization of existing processes and improvements in the utilization of process equipment that have been developed in recent years are presented in the book.

Novel Process Windows

Innovative Gates to Intensified and Sustainable Chemical Processes

Author: Volker Hessel,Dana Kralisch,Norbert Kockmann

Publisher: John Wiley & Sons

ISBN: 3527654844

Category: Technology & Engineering

Page: 344

View: 6528

This book introduces the concept of novel process windows, focusing on cost improvements, safety, energy and eco-efficiency throughout each step of the process. The first part presents the new reactor and process-related technologies, introducing the potential and benefit analysis. The core of the book details scenarios for unusual parameter sets and the new holistic and systemic approach to processing, while the final part analyses the implications for green and cost-efficient processing. With its practical approach, this is invaluable reading for those working in the pharmaceutical, fine chemicals, fuels and oils industries.

Mathematical and Physical Modeling of Materials Processing Operations

Author: Olusegun Johnso Ilegbusi,Manabu Iguchi,Walter E. Wahnsiedler

Publisher: CRC Press

ISBN: 9781584880172

Category: Technology & Engineering

Page: 512

View: 1241

The past few decades have brought significant advances in the computational methods and in the experimental techniques used to study transport phenomena in materials processing operations. However, the advances have been made independently and with competition between the two approaches. Mathematical models are easier and less costly to implement, but experiments are essential for verifying theoretical models. In Mathematical and Physical Modeling of Materials Processing Operations, the authors bridge the gap between mathematical modelers and experimentalists. They combine mathematical and physical modeling principles for materials processing operations simulation and use numerous examples to compare theoretical and experimental results. The modeling of transport processes is multi-disciplinary, involving concepts and principles not all of which can be associated with just one field of study. Therefore, the authors have taken care to ensure that the text is self-sustaining through the variety and breadth of topics covered. Beyond the usual topics associated with transport phenomena, the authors also include detailed discussion of numerical methods and implementation of process models, software and hardware selection and application, and representation of auxiliary relationships, including turbulence modeling, chemical kinetics, magnetohydrodynamics, and multi-phase flow. They also provide several correlations for representing the boundary conditions of fluid flow, heat transfer, and mass transfer phenomena. Mathematical and Physical Modeling of Materials Processing Operations is ideal for introducing these tools to materials engineers and researchers. Although the book emphasizes materials, some of the topics will prove interesting and useful to researchers in other fields of chemical and mechanical engineering.

Chemical Reactor Development

from Laboratory Synthesis to Industrial Production

Author: D. Thoenes

Publisher: Springer Science & Business Media

ISBN: 9780792330271

Category: Science

Page: 348

View: 4250

Chemical Reactor Development is written primarily for chemists and chemical engineers who are concerned with the development of a chemical synthesis from the laboratory bench scale, where the first successful experiments are performed, to the design desk, where the first commercial reactor is conceived. It is also written for those chemists and chemical engineers who are concerned with the further development of a chemical process with the objective of enhancing the performance of an existing industrial plant, as well as for students of chemistry and chemical engineering. In Part I, the `how' and the `why' of chemical reaction engineering are explained, particularly for those who are not familiar with this area. Part II deals with the effects of a number of physical phenomena on the outcome of chemical reactions, such as micro and meso-mixing and residence time distribution, mass transfer between two phases, and the formation of another phase, such as in precipitations. These scale-dependent effects are not only important in view of the conversion of chemical reactions, but also with regard to the selectivity, and in the case of solid products, to their morphology. In Part III, some applications are treated in a general way, including organic syntheses, the conversion and formation of inorganic solids, catalytic processes and polymerizations. The last chapter gives a review of the importance of the selectivity for product quality and for the purity of waste streams. For research chemists and chemical engineers whose work involves chemical reaction engineering. The book is also suitable as a supplementary graduate text.