Process Understanding

For Scale-Up and Manufacture of Active Ingredients

Author: Ian Houson

Publisher: John Wiley & Sons

ISBN: 3527637168

Category: Science

Page: 370

View: 9624

Process Understanding is the underpinning knowledge that allows the manufacture of chemical entities to be carried out routinely, robustly and to the required standard of quality. This area has gained in importance over the last few years, particularly due to the recent impetus from the USA`s Food and Drug Administration. This book covers the multidisciplinary aspects required for successful process design, safety, modeling, scale-up, PAT, pilot plant implementation, plant design as well the rapidly expanding area of outsourcing. In discussing what process understanding means to different disciplines and sectors throughout a product`s life cycle, this handbook and ready reference reveals the factors important to the development and manufacture of chemicals. The book focuses on the fundamental scientific understanding necessary. for a smoother technical transfer between the disciplines, leading to more effective and effi cient process development and manufacturing. A range of case studies are used to exemplify and illustrate the main issues raised. As a result, readers will appreciate that process understanding can deliver a real competitive advantage within the pharmaceuticals and fine chemicals industry. This book serves as an aid to meeting the stringent regulations required by the relevant authorities through demonstrable understanding of the underlying science.

Understanding Business


Author: David Barnes

Publisher: Psychology Press

ISBN: 9780415238618

Category: Business & Economics

Page: 225

View: 4369

Taking a systems perspective, this book enables the student to make sense of business behaviour by demonstrating how interrelated business processes determine the success of an organization.

Understanding Second Language Process

Author: Zhaohong Han,Eun Sung Park

Publisher: Multilingual Matters

ISBN: 1847690130

Category: Language Arts & Disciplines

Page: 256

View: 9804

This is a collection of 11 analytical and empirical studies on the process of second language acquisition, probing a wide array of issues, from transfer appropriate processing to L2 default processing strategies, among hearing or deaf learners of a variety of target languages.

Heart Wisdom Process

Understanding and Healing the Subconscious

Author: Paul P. Wong

Publisher: Createspace Independent Publishing Platform

ISBN: 9781973911173


Page: 126

View: 5862

Takes a vast and highly complex subject about human suffering and psychology and breaks it into simple, straightforward, and easy-to-apply practical knowledge. It can immediately help you become aware of the deeper subconscious causes of your life challenges. Shares insights from a decade of Paul Wong's journey with his life's struggles, studying the healing arts, working with clients globally, traveling the world teaching seminars, and learning from spiritual masters in the ashrams of India. Offers an unique self-inquiry and self-healing process that can be used for almost any life challenge. The Heart Wisdom Process is a synthesis of ancient Eastern principles and thousands of hours of trials and tribulations over the years. It is a must read for anyone who loves personal development and anyone from the professional fields of coaching, mental health, traditional or alternative therapies.

Gravel Bed Rivers 6

From Process Understanding to River Restoration

Author: H. Habersack,H. Piegay,M. Rinaldi

Publisher: Elsevier

ISBN: 9780080553597

Category: Science

Page: 836

View: 8739

Based on the interdisciplinary approaches between earth science, engineering, physical geography, ecology and management, this text focuses on the theoretical questions, case-studies, challenges, and constraints taken from river restoration. It is illustrated with reports of new ground-breaking research covering spatial and temporal scales of physical processes in river catchments, coupling catchment and fluvial processes, grain dynamics and fluvial forms and on geo-ecology and restoration in mountain gravel-bed river environments. Each chapter includes discussions and comments providing experience and feedback from the fundamental research. This book covers scales of analysis for gravel-bed rivers, physics and modeling of processes at local and point scales, sediment delivery and storage, eco-geography and eco-hydraulics, and channel management and restoration. * Major topics in the field are presented by recognized scientific leaders * Chapters cover theories, practices, and methodologies in river management and restoration * Interdisciplinary approach includes case-studies on new, ground-breaking research

The Strategic Planning Process

Understanding Strategy in Global Markets

Author: Marios Katsioloudes,Arpi K Abouhanian

Publisher: Taylor & Francis

ISBN: 1317623177

Category: Business & Economics

Page: 392

View: 9561

Strategic management is a field that has diversity in approach and scope, but relative homogeneity in pedagogy. This book, a refreshed edition of its successful predecessor, brings something different to the field, by concisely introducing it with a focus on doing business in the Middle East and North Africa. Supplemented by online case studies and other resources, the reader is exposed to a plethora of concepts, theories, practical implications, and experiential exercises in the strategic management process. The updated text explores key regional issues, including the "Arab Spring", economic recession, corporate social responsibility, the role of women in business and the rise of emerging economies. The reader is encouraged to look at the world in light of the challenges many organizations are facing around the globe. Features like "Stop and Think Critically" and "Focus" points throughout each chapter encourage and inspire a thoughtful reading of the text. This is a book designed to aid undergraduate and graduate students, as well as managers in both for-profit and non-profit sectors. The authors guides the reader through both new and ongoing issues in the field of strategic management, and allow them to foster a greater understanding of this ever-developing field.

Groundwater-surface Water Interaction

Process Understanding, Conceptualization and Modelling

Author: Corinna Abesser,Thorsten Wagener,Gunnar Nuetzmann

Publisher: International Assn of Hydrological Sciences


Category: Technology & Engineering

Page: 214

View: 8442

Selected papers from a symposium on A new Focus on Integrated Analysis of Groundwater-Surface Water Systems, held during the International Union of Geodesy and Geophysics XXIV General Assembly in Perugia, Italy, 11-13 July 2007.

Natural Processes

Understanding Metaphysics Without Substance

Author: Andrew M. Winters

Publisher: Springer

ISBN: 3319675702

Category: Philosophy

Page: 124

View: 5355

In thinking about ontology as the study of being or what fundamentally exists, we can adopt an ontology that either takes substances or processes as primary. There are, however, both commonsense and naturalistic reasons for not fully adopting a substance ontology, which indicate that we ought to suspend judgment with respect to the acceptance of a substance ontology. Doing so allows room to further explore other ontologies. In this book, Andrew M. Winters argues that there are both commonsense and naturalistic reasons for further pursuing a process ontology. Adopting a process ontology allows us to overcome many of the difficulties facing a substance ontology while also accommodating many of the phenomenon that substance ontologies were appealed to for explanation. Given these reasons, we have both commonsense and naturalistic reasons for pursuing and developing a metaphysics without substance.

Introduction to Graphic Design Methodologies and Processes

Understanding Theory and Application

Author: John Bowers

Publisher: John Wiley & Sons

ISBN: 1118157516

Category: Design

Page: 144

View: 4281

A concise, visually based introduction to graphic design methodologies Graphic design has emerged as a discipline complete with a body of scholarly literature devoted to its underlying theory. Introduction to Graphic Design Methodologies and Processes contributes to this expanding discourse by illustrating the value of qualitative and quantitative methodologies in guiding conceptual development in ways beyond those based on taste, style, and personal preference. Introduction to Graphic Design Methodologies and Processes: Introduces a range of practical methodologies pertinent to the interpreting, targeting, and creating of forms and messages Furthers the ability of designers by showing them how to design creatively, collaboratively, and strategically, and as a result, helps them move from form-makers to cultural participants—a transformative trend for design professionals Includes case studies with questions and answers contributed by a diverse group, including Second Story and Sol Sender As professional designers play more strategic roles, the need for material on design methodologies is growing. This concise, visually based introduction to the topic is the designer's definitive resource for defining their purpose, and producing work that is original, appropriate, responsible—and inspiring.

Understanding the Process of Aging

The Roles of Mitochondria: Free Radicals, and Antioxidants

Author: Lester Packer

Publisher: CRC Press

ISBN: 9780824717230

Category: Medical

Page: 384

View: 2798

This innovative reference explores a wide selection of topics associated with aging, providing a solid understanding of the significance and molecular basis of the aging process and charting the course of future research in the area. Stresses the interplay of mitochondria, mitochondrial DNA, oxidants, and antioxidants! Featuring the research of over 55 experts in the area, Understanding the Process of Aging covers the functions of nitric oxide and peroxynitrite in mitochondria integrates several views on the role of mitochondria in the development of apoptosis gives a quantitative analysis of mutations of mitochondrial DNA during human aging highlights mitochondrial free radical production introduces new roles of ubiquinone in mitochondrial functions offers new antioxidant-based complementary therapeutic strategies details aspects of intact cells and whole organisms in health and disease and more! Featuring over 1800 references, tables, drawings, and photographs, Understanding the Process of Aging benefits nutritionists and dieticians, geriatricians, cell and molecular biologists, chemists and biochemists, pharmacologists, biotechnologists, neurologists, cardiologists, oncologists, dermatologists, and graduate and medical school students in these disciplines.

Understanding the Linux Kernel

From I/O Ports to Process Management

Author: Daniel P. Bovet,Marco Cesati

Publisher: "O'Reilly Media, Inc."

ISBN: 9780596554910

Category: Computers

Page: 944

View: 2175

In order to thoroughly understand what makes Linux tick and why it works so well on a wide variety of systems, you need to delve deep into the heart of the kernel. The kernel handles all interactions between the CPU and the external world, and determines which programs will share processor time, in what order. It manages limited memory so well that hundreds of processes can share the system efficiently, and expertly organizes data transfers so that the CPU isn't kept waiting any longer than necessary for the relatively slow disks. The third edition of Understanding the Linux Kernel takes you on a guided tour of the most significant data structures, algorithms, and programming tricks used in the kernel. Probing beyond superficial features, the authors offer valuable insights to people who want to know how things really work inside their machine. Important Intel-specific features are discussed. Relevant segments of code are dissected line by line. But the book covers more than just the functioning of the code; it explains the theoretical underpinnings of why Linux does things the way it does. This edition of the book covers Version 2.6, which has seen significant changes to nearly every kernel subsystem, particularly in the areas of memory management and block devices. The book focuses on the following topics: Memory management, including file buffering, process swapping, and Direct memory Access (DMA) The Virtual Filesystem layer and the Second and Third Extended Filesystems Process creation and scheduling Signals, interrupts, and the essential interfaces to device drivers Timing Synchronization within the kernel Interprocess Communication (IPC) Program execution Understanding the Linux Kernel will acquaint you with all the inner workings of Linux, but it's more than just an academic exercise. You'll learn what conditions bring out Linux's best performance, and you'll see how it meets the challenge of providing good system response during process scheduling, file access, and memory management in a wide variety of environments. This book will help you make the most of your Linux system.

Understanding the Creative Process

Author: Rigoberto Garcia


ISBN: 1430325534

Category: Business & Economics

Page: 188

View: 4881

As a Project Manager you must have a clear understanding of how to manage and encourage the creative process. Project managers alike are geared toward people management and not creative cycles. Most times they find themselves unable to mitigate conflict and the creative process fails. In my book, I introduced basic management concepts designed to manage the creative environment while setting the stage for innovation. By managing the creative environment, a Project Manager will lay the groundwork for the innovation without forsaking other basic management cycles. Since the main goal of a Project Manager should be to manage scope and the strategical heading of a project; he or she must prove themselves to be a capable leader, able to understand the needs of the team essentially when it comes to how to care for and mitigate innovation in a project environment prior to initiating a creative brainstorming session.

Understanding Assessment in the Special Education Process

A Step-by-Step Guide for Educators

Author: Roger Pierangelo,George Giuliani

Publisher: Skyhorse Publishing, Inc.

ISBN: 1510701338

Category: Education

Page: 136

View: 2900

An ideal step-by-step reference for instructors who have not had specific training in assessing students with special needs, Understanding Assessment in the Special Education Process helps educators make the most effective use of available assessment options.