Scale-up in Chemical Engineering

Author: Marko Zlokarnik

Publisher: John Wiley & Sons

ISBN: 3527607765

Category: Science

Page: 296

View: 5352

Covering the important task of the scale-up of processes from the laboratory to the production scale, this easily comprehensible and transparent book is divided into two sections. The first part details the theoretical principles, introducing the subject for readers without a profound prior knowledge of mathematics. It discusses the fundamentals of dimensional analysis, the treatment of temperature-dependent and rheological material values and scale-up where model systems or not available or only partly similar. All this is illustrated by 20 real-world examples, while 25 exercises plus solutions new to this edition practice and monitor learning. The second part presents the individual basic operations and covers the fields of mechanical, thermal, and chemical process engineering with respect to dimensional analysis and scale-up. The rules for scale-up are given and discussed for each operation. Other additions to this second edition are dimensional analysis of pelleting processes, and a historical overview of dimensional analysis and modeling, while all the chapters have been updated to take the latest literature into account. Written by a specialist with more than 40 years of experience in the industry, this book is specifically aimed at students as well as practicing engineers, chemists and process engineers already working in the field.

Dimensional Analysis and Scale-up in Chemical Engineering

Author: Marko Zlokarnik

Publisher: Springer Science & Business Media

ISBN: 3642766730

Category: Science

Page: 178

View: 1511

Contemporary Chemical Process Engineers face complex design and research problems. Temperature-dependent physical properties and non-Newtonian flow behavior of substances in a process cannot be predicted by numerical mathematics. Scaling-up equipment for processing can often only be done with partial similarity methods. Standard textbooks often neglect topics like dimensional analysis, theory of similarity and scale-up. This book fills this gap! It is aimed both at university students and the process engineer. It presents dimensional analysis very comprehensively with illustrative examples of mechanical, thermal and chemical processes.

Chemical Projects Scale Up

How to go from Laboratory to Commercial

Author: Joe M. Bonem

Publisher: Elsevier

ISBN: 0128137282

Category: Technology & Engineering

Page: 232

View: 9262

Chemical Projects Scale Up: How to Go from Laboratory to Commercial covers the chemical engineering steps necessary for taking a laboratory development into the commercial world. The book includes the problems associated with scale up, equipment sizing considerations, thermal characteristics associated with scale up, safety areas to consider, recycling considerations, operability reviews and economic viability. In addition to the process design aspects of commercializing the laboratory development, consideration is given to the utilization of a development in an existing plant. Explains how heat removal for exothermic reactions can be scaled up Outlines how a reactor can be sized from batch kinetic data Discusses how the plant performance of a new catalyst can be evaluated Presents how the economics of a new product/process can be developed Discusses the necessary evaluation of recycling in commercial plants

Scale-up Methodology for Chemical Processes

Author: Jean-Paul Euzen,Pierre Trambouze,Jean-Pierre Wauquier

Publisher: Editions TECHNIP

ISBN: 9782710806462

Category: Technology & Engineering

Page: 240

View: 1697

Having gained considerable experience in process development at the Institut FranCais du PEtrole, the authors present a design framework, a review of the available means of investigation, and several examples illustrating their methodology of industrial process scale up. The salient feature of the book is the fact that it addresses a subject which is vital in view of its economic repercussions, yet relatively unknown in technical and scientific circles, due to the confidentiality surrounding it.Contents: 1. Main guidelines of the methodology. 2. Various types of model. 3. Pilot plants and mock-ups. 4. Experimental techniques. 5. Applications to industrial process development. 6. Conclusions. References. Index.

Chemical Reactor Design, Optimization, and Scaleup

Author: E. Bruce Nauman

Publisher: John Wiley & Sons

ISBN: 0470282061

Category: Technology & Engineering

Page: 656

View: 1382

The classic reference, now expanded and updated Chemical Reactor Design, Optimization, and Scaleup is the authoritative sourcebook on chemical reactors. This new Second Edition consolidates the latest information on current optimization and scaleup methodologies, numerical methods, and biochemical and polymer reactions. It provides the comprehensive tools and information to help readers design and specify chemical reactors confidently, with state-of-the-art skills. This authoritative guide: Covers the fundamentals and principles of chemical reactor design, along with advanced topics and applications Presents techniques for dealing with varying physical properties in reactors of all types and purposes Includes a completely new chapter on meso-, micro-, and nano-scale reactors that addresses such topics as axial diffusion in micro-scale reactors and self-assembly of nano-scale structures Explains the method of false transients, a numerical solution technique Includes suggestions for further reading, problems, and, when appropriate, scaleup or scaledown considerations at the end of each chapter to illustrate industrial applications Serves as a ready reference for explained formulas, principles, and data This is the definitive hands-on reference for practicing professionals and an excellent textbook for courses in chemical reactor design. It is an essential resource for chemical engineers in the process industries, including petrochemicals, biochemicals, microelectronics, and water treatment.

Concepts of Chemical Engineering 4 Chemists

Author: Stefaan J. R. Simons,Royal Society of Chemistry (Great Britain)

Publisher: Royal Society of Chemistry

ISBN: 0854049517

Category: Science

Page: 350

View: 642

Based on the popular course of the same title, Concepts of Chemical Engineering 4 Chemists outlines the basic aspects of chemical engineering for chemistry professionals. It clarifies the terminology used and explains the systems methodology approach to process design and operation for chemists with limited chemical engineering knowledge. The book provides practical insights into all areas of chemical engineering, including such aspects as pump design and the measurement of key process variables. The calculation of design parameters, such as heat and mass transfer coefficients, and reaction scale-up are also discussed, as well as hazard analysis, project economics and process control. Designed as a reference guide, it is fully illustrated and includes worked examples as well as extensive reference and bibliography sections. Concepts of Chemical Engineering 4 Chemists is ideal for those who either work alongside chemical engineers or who are embarking on chemical engineering-type projects.

Chemical Engineering in the Pharmaceutical Industry

R&D to Manufacturing

Author: David J. am Ende

Publisher: John Wiley & Sons

ISBN: 1118088107

Category: Technology & Engineering

Page: 904

View: 5706

This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences. Many of the experimental methods related to pharmaceutical process development are learned on the job. This book is intended to provide many of those important concepts that R&D Engineers and manufacturing Engineers should know and be familiar if they are going to be successful in the Pharmaceutical Industry. These include basic analytics for quantitation of reaction components– often skipped in ChE Reaction Engineering and kinetics books. In addition Chemical Engineering in the Pharmaceutical Industry introduces contemporary methods of data analysis for kinetic modeling and extends these concepts into Quality by Design strategies for regulatory filings. For the current professionals, in-silico process modeling tools that streamline experimental screening approaches is also new and presented here. Continuous flow processing, although mainstream for ChE, is unique in this context given the range of scales and the complex economics associated with transforming existing batch-plant capacity. The book will be split into four distinct yet related parts. These parts will address the fundamentals of analytical techniques for engineers, thermodynamic modeling, and finally provides an appendix with common engineering tools and examples of their applications.

Scaling Chemical Processes

Practical Guides in Chemical Engineering

Author: Jonathan Worstell

Publisher: Butterworth-Heinemann

ISBN: 0128047690

Category: Technology & Engineering

Page: 186

View: 465

Scaling Chemical Processes: Practical Guides in Chemical Engineering is one of a series of short texts that each provides a focused introductory view on a single subject. The full library spans the main topics in the chemical process industries for engineering professionals who require a basic grounding in various related topics. They are ‘pocket publications’ that the professional engineer can easily carry with them or access electronically while working. Each text is highly practical and applied, and presents first principles for engineers who need to get up to speed in a new area fast. The focused facts provided in each guide will help you converse with experts in the field, attempt your own initial troubleshooting, check calculations, and solve rudimentary problems. This book discusses scaling chemical processes from a laboratory through a pilot plant to a commercial plant. It bases scaling on similarity principles and uses dimensional analysis to derive the dimensionless parameters necessary to ensure a successful chemical process development program. This series is fully endorsed and co-branded by the IChemE, and they help to promote the series. Offers practical, short, concise information on the basics to help you get an answer or teach yourself a new topic quickly Includes industry examples to help you solve real world problems Provides key facts for professionals in convenient single subject volumes Discusses scaling chemical processes from a laboratory through a pilot plant to a commercial plant

Industrial Process Scale-up

A Practical Innovation Guide from Idea to Commercial Implementation

Author: Jan Harmsen

Publisher: Elsevier

ISBN: 0444627391

Category: Technology & Engineering

Page: 112

View: 2859

This book will help industrial process innovators in research, development and commercial start-up to assess the risks of commercial-scale implementation and provide them with practical guidelines and methods to reduce the risks to acceptable levels. The book can also be used in co-operation with industrial R&D people and academic researchers to shape open innovation programs and in education as a reference book for process innovation courses. Offers easily accessible, step-by-step, and concise guidelines for industrial process scale-up Explains each stage of the innovation funnel: research, development, demonstration, commercial implementation for any process type and branch Based on industrial experiences and practices, which reduces the risks of commercial scale implementation of new processes to acceptable levels and reduces cost and time of process innovation Very clear, attractive layout, using text boxes that contain clarifying notes and additional information on specific topics, which makes it a quick reference of main subjects and additional information

The Pilot Plant Real Book

A Unique Handbook for the Chemical Process Industry

Author: Francis X. McConville

Publisher: Fxm Engineering & Design

ISBN: 9780972176927

Category: Science

Page: 320

View: 8340

Food Processing Operations and Scale-up

Author: Kenneth J. Valentas,J. Peter Clark,Leon Levin

Publisher: CRC Press

ISBN: 9780824782795

Category: Technology & Engineering

Page: 408

View: 1500

Intended for students and practitioners who have a basic education in chemical engineering or food science. Contains basic information in each area and describes some of the fundamental ideas of processing development and design. Examines the food industry structure, how it works, consumer products,

Chemical Process Equipment

Selection and Design

Author: James R. Couper,W. Roy Penney,James R. Fair, PhD

Publisher: Elsevier

ISBN: 0123972361

Category: Technology & Engineering

Page: 864

View: 5819

Chemical Process Equipment is a results-oriented reference for engineers who specify, design, maintain or run chemical and process plants. This book delivers information on the selection, sizing and operation of process equipment in a format that enables quick and accurate decision making on standard process and equipment choices, saving time, improving productivity, and building understanding. Coverage emphasizes common real-world equipment design rather than experimental or esoteric and focuses on maximizing performance. Legacy reference for chemical and related engineers who work with vendors to design, specify and make final equipment selection decisions Copious examples of successful applications, with supporting schematics and data to illustrate the functioning and performance of equipment Provides equipment rating forms and manufacturers’ data, worked examples, valuable shortcut methods, and rules of thumb to demonstrate and support the design process Heavily illustrated with line drawings and schematics to aid understanding, as well as graphs and tables to illustrate performance data

Mesoscale Modeling in Chemical Engineering

Author: N.A

Publisher: Academic Press

ISBN: 0128039310

Category: Technology & Engineering

Page: 426

View: 1874

Mesoscale Modeling in Chemical Engineering, a volume in the Advances in Chemical Engineering series provides the reader with personal views of authorities in the field. Subjects covered are not limited to the classical chemical engineering disciplines, with contributions connecting chemical engineering to related scientific fields, thus providing new ideas for additional thought. The book balances well developed areas such as process industry, transformation of materials, energy, and environmental issues with areas where applications of chemical engineering are more recent or emerging. Contains reviews by leading authorities in the respective areas Presents Up-to-date reviews of latest techniques in modeling of catalytic processes Includes a mix of US and European authors, as well as academic/industrial/research institute perspectives Contains the critical connections between computation and experimental methods

Industrial Scale Natural Products Extraction

Author: Hans-Jörg Bart,Stephan Pilz

Publisher: John Wiley & Sons

ISBN: 3527635130

Category: Technology & Engineering

Page: 314

View: 2081

Covering the latest technologies in process engineering, this handbook and ready reference features high pressure processing, alternative solvents and processes, extraction technologies and biotransformations -- describing greener, more efficient and sustainable techniques. The result is an expert account of engineering details from lab-scale experiments to large-scale industrial design. The major focus is on the engineering aspects of extraction with organic and supercritical solvents, ionic liquids or surfactant solutions, and is supplemented by aspects of both up- and downstream processing, biotransformation, as well as a survey of typical products in food, pharmaceutical and cosmetic applications. This is rounded off by market developments, economic considerations and regulations requirements in the field Authored by experts from leading industrial and academic institutions, this is essential reading for the hands-on scientist and office manager alike.

Modeling of Chemical Kinetics and Reactor Design

Author: A. Kayode Coker

Publisher: Gulf Professional Publishing

ISBN: 9780884154815

Category: Technology & Engineering

Page: 1096

View: 2112

Selecting the best type of reactor for any particular chemical reaction, taking into consideration safety, hazard analysis, scale-up, and many other factors is essential to any industrial problem. An understanding of chemical reaction kinetics and the design of chemical reactors is key to the success of the of the chemist and the chemical engineer in such an endeavor. This valuable reference volume conveys a basic understanding of chemical reactor design methodologies, incorporating control, hazard analysis, and other topics not covered in similar texts. In addition to covering fluid mixing, the treatment of wastewater, and chemical reactor modeling, the author includes sections on safety in chemical reaction and scale-up, two topics that are often neglected or overlooked. As a real-world introduction to the modeling of chemical kinetics and reactor design, the author includes a case study on ammonia synthesis that is integrated throughout the text. The text also features an accompanying CD, which contains computer programs developed to solve modeling problems using numerical methods. Students, chemists, technologists, and chemical engineers will all benefit from this comprehensive volume. Shows readers how to select the best reactor design, hazard analysis, and safety in design methodology Features computer programs developed to solve modeling problems using numerical methods

Bioprocess Engineering

An Introductory Engineering and Life Science Approach

Author: Kim Gail Clarke

Publisher: Elsevier

ISBN: 1782421688

Category: Science

Page: 266

View: 8957

Biotechnology is an expansive field incorporating expertise in both the life science and engineering disciplines. In biotechnology, the scientist is concerned with developing the most favourable biocatalysts, while the engineer is directed towards process performance, defining conditions and strategies that will maximize the production potential of the biocatalyst. Increasingly, the synergistic effect of the contributions of engineering and life sciences is recognised as key to the translation of new bioproducts from the laboratory bench to commercial bioprocess. Fundamental to the successful realization of the bioprocess is a need for process engineers and life scientists competent in evaluating biological systems from a cross-disciplinary viewpoint. Bioprocess engineering aims to generate core competencies through an understanding of the complementary biotechnology disciplines and their interdependence, and an appreciation of the challenges associated with the application of engineering principles in a life science context. Initial chapters focus on the microbiology, biochemistry and molecular biology that underpin biocatalyst potential for product accumulation. The following chapters develop kinetic and mass transfer principles that quantify optimum process performance and scale up. The text is wide in scope, relating to bioprocesses using bacterial, fungal and enzymic biocatalysts, batch, fed-batch and continuous strategies and free and immobilised configurations. Details the application of chemical engineering principles for the development, design, operation and scale up of bioprocesses Details the knowledge in microbiology, biochemistry and molecular biology relevant to bioprocess design, operation and scale up Discusses the significance of these life sciences in defining optimum bioprocess performance

Pilot Plants and Scale-up of Chemical Processes

Author: William Hoyle

Publisher: Royal Society of Chemistry

ISBN: N.A

Category: Science

Page: 97

View: 1928

One of the biggest challenges facing today's chemist and chemical engineer is the translation of bench chemistry to the pilot plant. This book provides expert insights into current best practice, and will prove an indispensable manual for all those involved in pilot plant design and scale-up implementation - process chemists, engineers and managers alike. The international expertise of the contributors covers a wide range of topics, and new material covered includes: the removal of heavy metals from effluent, heat flow calorimetry, low temperature processes, good manufacturing practice in pilot plants, design issues, the use of statistical methods in the running of pilot plants. Pilot Plants and Scale-Up of Chemical Processes is a must for all those who are, and wish to remain, expert in the field, providing for the first time in print, a comprehensive and unique perspective of pilot plant production.