The Path to the Double Helix

The Discovery of DNA

Author: Robert Olby

Publisher: Courier Corporation

ISBN: 0486166597

Category: Science

Page: 560

View: 8800

Written by a noted historian of science, this in-depth account traces how Watson and Crick achieved one of science's most dramatic feats: their 1953 discovery of the molecular structure of DNA.

Francis Crick

Hunter of Life's Secrets

Author: Robert Cecil Olby

Publisher: N.A

ISBN: N.A

Category: Biography & Autobiography

Page: 538

View: 3199

"In Francis Crick: Hunter of Life's Secrets, Robert Olby presents a full-length intellectual biography of Crick's life in science. After early life in Northampton, Crick gained experience as a scientist for the Royal Navy during World War II, before beginning academic studies in biophysics. His pioneering work in molecular biology in the 1950s and 1960s took place in Cambridge, and was followed by his move to the United States in 1976 and his work in neuroscience at the Salk Institute. Olby's detailed exploration of Crick's scientific life up to the famous 1953 discovery and beyond provides a clear demonstration of how chance does indeed favor the prepared mind.".

Double Helix

The Quest to Uncover the Structure of DNA

Author: Glen Phelan

Publisher: National Geographic Books

ISBN: 9780792255413

Category: Juvenile Nonfiction

Page: 59

View: 9105

Presents the scientific knowledge and breakthroughs that led to the discovery of DNA and its structure.

Molecular Biology of the Gene

Author: James D. Watson,Tania A. Baker,Stephen P. Bell,Alexander Gann,Michael Levine,Richard Losick

Publisher: Pearson Higher Ed

ISBN: 032189670X

Category: Science

Page: 880

View: 1099

This is the eBook of the printed book and may not include any media, website access codes, or print supplements that may come packaged with the bound book. Now completely up-to-date with the latest research advances, the Seventh Edition of James D. Watson’s classic book, Molecular Biology of the Gene retains the distinctive character of earlier editions that has made it the most widely used book in molecular biology. Twenty-two concise chapters, co-authored by six highly distinguished biologists, provide current, authoritative coverage of an exciting, fast-changing discipline.

DNA Pioneer

James Watson and the Double Helix

Author: Joyce Baldwin

Publisher: Walker & Company

ISBN: 9780802782977

Category: Biography & Autobiography

Page: 136

View: 8155

Traces the life of the research scientist who helped discover the structure of DNA, and discusses his work in cancer research and with the National Center for Human Genome Research

The Double Helix

A Personal Account of the Discovery of the Structure of DNA

Author: James D. Watson

Publisher: Simon and Schuster

ISBN: 0743219171

Category: Science

Page: 256

View: 2418

The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

50 Years of DNA

Author: J. Clayton,C. Dennis

Publisher: Springer

ISBN: 1137117818

Category: Literary Criticism

Page: 139

View: 5902

Crick and Watson's discovery of the structure of DNA fifty years ago marked one of the great turning points in the history of science. Biology, immunology, medicine and genetics have all been radically transformed in the succeeding half-century, and the double helix has become an icon of our times. This fascinating exploration of a scientific phenomenon provides a lucid and engaging account of the background and context for the discovery, its significance and afterlife, while a series of essays by leading scientists, historians and commentators offers uniquely individual perspectives on DNA and its impact on modern science and society.

Avoid Boring People

Lessons from a Life in Science

Author: James D. Watson

Publisher: Vintage

ISBN: 0307481794

Category: Biography & Autobiography

Page: 368

View: 3678

From Nobel Prize-winning scientist James D. Watson, a living legend for his work unlocking the structure of DNA, comes this candid and entertaining memoir, filled with practical advice for those starting out their academic careers. In Avoid Boring People, Watson lays down a life’s wisdom for getting ahead in a competitive world. Witty and uncompromisingly honest, he shares his thoughts on how young scientists should choose the projects that will shape their careers, the supreme importance of collegiality, and dealing with competitors within the same institution. It’s an irreverent romp through Watson’s colorful career and an indispensable guide to anyone interested in nurturing the life of the mind. From the Trade Paperback edition.

A Life Decoded

My Genome: My Life

Author: J. Craig Venter

Publisher: Penguin

ISBN: 1101202564

Category: Biography & Autobiography

Page: 400

View: 7437

The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.

Rosalind Franklin and DNA

Author: Anne Sayre

Publisher: W. W. Norton & Company

ISBN: 9780393320442

Category: Biography & Autobiography

Page: 221

View: 1100

Presents the frequently overlooked story of the woman who helped discover the double helix structure of DNA, detailing the contributions of scientist Rosalind Franklin to the work of Watson, Crick, and Wilkins.

Meselson, Stahl, and the Replication of DNA

A History of "The Most Beautiful Experiment in Biology"

Author: Frederic Lawrence Holmes

Publisher: Yale University Press

ISBN: 9780300129663

Category: Science

Page: 528

View: 3753

In 1957 two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a “most beautiful” experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple, Frederic L. Holmes shows in this masterful account of Meselson and Stahl’s quest. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research--its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. Holmes uses research logs, experimental films, correspondence, and interviews with the participants to record the history of Meselson and Stahl’s research, from their first thinking about the problem through the publication of their dramatic results. Holmes also reviews the scientific community’s reception of the experiment, the experiment’s influence on later investigations, and the reasons for its reputation as an exceptionally beautiful experiment.

DNA

The Story of the Genetic Revolution

Author: James D. Watson,Andrew James Berry,Kevin Davies

Publisher: Knopf

ISBN: 0385351186

Category: Medical

Page: 487

View: 8378

Updated edition of: DNA: the secret of life.

DNA

The Secret of Life

Author: James D. Watson,Andrew Berry

Publisher: Knopf

ISBN: 0307521486

Category: Science

Page: 464

View: 2186

Fifty years ago, James D. Watson, then just twentyfour, helped launch the greatest ongoing scientific quest of our time. Now, with unique authority and sweeping vision, he gives us the first full account of the genetic revolution—from Mendel’s garden to the double helix to the sequencing of the human genome and beyond. Watson’s lively, panoramic narrative begins with the fanciful speculations of the ancients as to why “like begets like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel first deduced the basic laws of inheritance. But genetics as we recognize it today—with its capacity, both thrilling and sobering, to manipulate the very essence of living things—came into being only with the rise of molecular investigations culminating in the breakthrough discovery of the structure of DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s graceful curves was the key to a whole new science. Having shown that the secret of life is chemical, modern genetics has set mankind off on a journey unimaginable just a few decades ago. Watson provides the general reader with clear explanations of molecular processes and emerging technologies. He shows us how DNA continues to alter our understanding of human origins, and of our identities as groups and as individuals. And with the insight of one who has remained close to every advance in research since the double helix, he reveals how genetics has unleashed a wealth of possibilities to alter the human condition—from genetically modified foods to genetically modified babies—and transformed itself from a domain of pure research into one of big business as well. It is a sometimes topsy-turvy world full of great minds and great egos, driven by ambitions to improve the human condition as well as to improve investment portfolios, a world vividly captured in these pages. Facing a future of choices and social and ethical implications of which we dare not remain uninformed, we could have no better guide than James Watson, who leads us with the same bravura storytelling that made The Double Helix one of the most successful books on science ever published. Infused with a scientist’s awe at nature’s marvels and a humanist’s profound sympathies, DNA is destined to become the classic telling of the defining scientific saga of our age.

Heraclitean Fire

Sketches from a Life Before Nature

Author: Erwin Chargaff

Publisher: Paul & Company Pub Consortium

ISBN: N.A

Category: Science

Page: 252

View: 911

The eminent biochemist reflects on his life and work in Vienna and in America, shedding light on his DNA research and the work and opinions that led to his reputation as a maverick

The Social Life of DNA

Race, Reparations, and Reconciliation After the Genome

Author: Alondra Nelson

Publisher: Beacon Press

ISBN: 0807033022

Category: Social Science

Page: 216

View: 5950

The unexpected story of how genetic testing is affecting race in America We know DNA is a master key that unlocks medical and forensic secrets, but its genealogical life is both revelatory and endlessly fascinating. Tracing genealogy is now the second-most popular hobby amongst Americans, as well as the second-most visited online category. This billion-dollar industry has spawned popular television shows, websites, and Internet communities, and a booming heritage tourism circuit. The tsunami of interest in genetic ancestry tracing from the African American community has been especially overwhelming. In The Social Life of DNA, Alondra Nelson takes us on an unprecedented journey into how the double helix has wound its way into the heart of the most urgent contemporary social issues around race. For over a decade, Nelson has deeply studied this phenomenon. Artfully weaving together keenly observed interactions with root-seekers alongside illuminating historical details and revealing personal narrative, she shows that genetic genealogy is a new tool for addressing old and enduring issues. In The Social Life of DNA, she explains how these cutting-edge DNA-based techniques are being used in myriad ways, including grappling with the unfinished business of slavery: to foster reconciliation, to establish ties with African ancestral homelands, to rethink and sometimes alter citizenship, and to make legal claims for slavery reparations specifically based on ancestry. Nelson incisively shows that DNA is a portal to the past that yields insight for the present and future, shining a light on social traumas and historical injustices that still resonate today. Science can be a crucial ally to activism to spur social change and transform twenty-first-century racial politics. But Nelson warns her readers to be discerning: for the social repair we seek can’t be found in even the most sophisticated science. Engrossing and highly original, The Social Life of DNA is a must-read for anyone interested in race, science, history and how our reckoning with the past may help us to chart a more just course for tomorrow. From the Hardcover edition.

Life's Greatest Secret

The Race to Crack the Genetic Code

Author: Matthew Cobb

Publisher: Basic Books

ISBN: 0465062660

Category: Science

Page: 464

View: 9959

Everyone has heard of the story of DNA as the story of Watson and Crick and Rosalind Franklin, but knowing the structure of DNA was only a part of a greater struggle to understand life’s secrets. Life’s Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had farreaching consequences for how we understand ourselves and our place in the natural world, and for how we might take control of our (and life’s) future. Life’s Greatest Secret mixes remarkable insights, theoretical dead-ends, and ingenious experiments with the swift pace of a thriller. From New York to Paris, Cambridge, Massachusetts, to Cambridge, England, and London to Moscow, the greatest discovery of twentieth-century biology was truly a global feat. Biologist and historian of science Matthew Cobb gives the full and rich account of the cooperation and competition between the eccentric characters—mathematicians, physicists, information theorists, and biologists—who contributed to this revolutionary new science. And, while every new discovery was a leap forward for science, Cobb shows how every new answer inevitably led to new questions that were at least as difficult to answer: just ask anyone who had hoped that the successful completion of the Human Genome Project was going to truly yield the book of life, or that a better understanding of epigenetics or “junk DNA” was going to be the final piece of the puzzle. But the setbacks and unexpected discoveries are what make the science exciting, and it is Matthew Cobb’s telling that makes them worth reading. This is a riveting story of humans exploring what it is that makes us human and how the world works, and it is essential reading for anyone who’d like to explore those questions for themselves.

Molecular Biology of the Cell

Author: Bruce Alberts

Publisher: Garland Science

ISBN: 1317563743

Category: Science

Page: 1464

View: 5382

As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

Life at the Speed of Light

From the Double Helix to the Dawn of Digital Life

Author: J. Craig Venter

Publisher: Penguin

ISBN: 0143125907

Category: Science

Page: 224

View: 2820

The author of A Life Decoded explains how his team's achievement with sequencing the human genome has launched an important age of biological research, revealing a growing potential for enabling humans to adapt and evolve for long-term survival and environmental improvement.

Rosalind Franklin

The Dark Lady of DNA

Author: Brenda Maddox

Publisher: Harper Collins

ISBN: 0062283502

Category: Biography & Autobiography

Page: 416

View: 1414

In 1962, Maurice Wilkins, Francis Crick, and James Watson received the Nobel Prize, but it was Rosalind Franklin's data and photographs of DNA that led to their discovery. Brenda Maddox tells a powerful story of a remarkably single-minded, forthright, and tempestuous young woman who, at the age of fifteen, decided she was going to be a scientist, but who was airbrushed out of the greatest scientific discovery of the twentieth century.

The Cosmic Serpent

Author: Jeremy Narby

Publisher: Penguin

ISBN: 1101494352

Category: Science

Page: 272

View: 2160

This adventure in science and imagination, which the Medical Tribune said might herald "a Copernican revolution for the life sciences," leads the reader through unexplored jungles and uncharted aspects of mind to the heart of knowledge.In a first-person narrative of scientific discovery that opens new perspectives on biology, anthropology, and the limits of rationalism, The Cosmic Serpent reveals how startlingly different the world around us appears when we open our minds to it.