Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues

Author: Elaine Sarkin Jaffe

Publisher: IARC

ISBN: 9789283224112

Category: Genetics

Page: 351

View: 9046

This is the third volume in the new World Health Organization series on histological and genetic typing of tumours. Tumours of the haematopoietic and lymphoid tissues are covered. This was a collaborative project of the European Association for Haematolpathology and the Society for Haematopathology and others. The WHO classification is based on the principles defined in the Revised European-American Classification of Lymphoid Neoplasms (REAL) classification. Over 50 pathologists from around the world were involved in the project and proponents of all major lymphoma and leukaemia classifications have agreed to accept the WHO as the standard classification of haematological malignancies. So this classification represents the first true world wide concensus of haematologic malignancies. Colour photographs, magnetic resonance and ultrasound images and CT scans are included.

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues

Author: E. Campo,N. L. Harris,S. A. Pileri,E. S. Jaffe,H. Stein,J. Thiele

Publisher: IARC Who Classification of Tum

ISBN: 9789283244943

Category: Medical

Page: 586

View: 2505

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues is a Revised Fourth Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants further include new ICD-O codes, epidemiology, clinical features, macroscopy, prognosis, and predictive factors. This classification, prepared by 132 authors from 23 countries, contains about 1300 color images and tables and more than 4500 references.

Pathologie

Hämatologie, inkl. Lymphknoten, Milz, Thymus

Author: Alfred Christian Feller,Günter Klöppel,Wolfgang Remmele,Hans Kreipe

Publisher: Springer

ISBN: 9783540851837

Category: Medical

Page: 500

View: 1369

Blood Cells

A Practical Guide

Author: Barbara J. Bain

Publisher: John Wiley & Sons

ISBN: 111881729X

Category: Medical

Page: 504

View: 9439

Enables both the haematologist and laboratory scientist to identify blood cell features, from the most common to the more obscure Provides essential information on methods of collection, blood film preparation and staining, together with the principles of manual and automated blood counts Completely revised and updated, incorporating much newly published information: now includes advice on further tests when a specific diagnosis is suspected 400 high quality photographs to aid with blood cell identification Highlights the purpose and clinical relevance of haematology laboratory tests throughout

Dacie and Lewis Practical Haematology

Expert Consult: Online and Print

Author: Barbara J. Bain,Imelda Bates,Mike A Laffan,S. Mitchell Lewis

Publisher: Elsevier Health Sciences

ISBN: 0702050253

Category: Medical

Page: 668

View: 4185

Highly Commended at 2012 BMA awards in Internal Medicine Category. Recognized worldwide as the standard reference work, Dacie & Lewis Practical Haematology is a must have reference for any haematology laboratory. It covers all of the techniques used in the investigation of patients with blood disorders, including the latest technologies as well as the tried and true manual methods of measurement. It discusses the principles of each test, possible causes of error, the rationale for choosing one method over another and the interpretation, significance and clinical relevance of these findings. Each chapter conforms to a template, providing quick access to key information

Clinical Cytogenetics, An Issue of Clinics in Laboratory Medicine - E-Book

Author: Caroline Astbury

Publisher: Elsevier Health Sciences

ISBN: 1455709352

Category: Medical

Page: 385

View: 1619

This issue of Clinics in Laboratory Medicine, Guest Edited by Caroline Astbury, PhD, FACMG, will focus on Cytogenetics, with topics including: Chronic lymphocytic leukemia; Acute lymphocytic leukemia; Acute myelogenous leukemia; Chronic myelogenous leukemia; Plasma cell myeloma; Lymphomas; Solid tumors; Myelodysplastic syndromes; SNP arrays in clinical practice; Prenatal arrays; FISH (including Paraffin-embedded (PET) FISH); New and old microdeletion and microduplication syndromes; Sex chromosome and sex chromosome abnormalities; Autosomal aneuploidy; Microarray-CGH interpretation and Genomic Integrity; Structural chromosome rearrangements and complex chromosome rearrangements; and UPD/imprinting.

Rosai and Ackerman's Surgical Pathology E-Book

Author: Juan Rosai

Publisher: Elsevier Health Sciences

ISBN: 032308804X

Category: Medical

Page: 2892

View: 491

Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity. Compare your findings to more than 3,300 outstanding illustrations that capture the characteristic presentation of every type of lesion. Avoid diagnostic pitfalls using Dr. Rosai's expert observations on what to look for, what to be careful about, and which presentations can be misleading. Find quick answers on tumor staging, quality control procedures, and the handling of gross specimens through valuable appendices. Make optimal use of all the very latest advances including our increased understanding of the genetic basis of inherited and acquired disease, the newest molecular genetic and immunohistochemical techniques, and the most recent WHO disease classification schemes.

Lymph Nodes

Author: Alexandra Harrington, MD,Steven H. Kroft, MD,Horatiu Olteanu, MD, PhD

Publisher: Demos Medical Publishing

ISBN: 1617050202

Category: Medical

Page: 184

View: 7010

The Demos Surgical Pathology Guides series presents in summary and visual form the basic knowledge base that every practicing pathologist needs every working day. Series volumes cover the major specialty areas of surgical pathology, and coverage emphasizes the key entities and diagnoses that pathologists will see in practice, and that they must know whether in training or practice. The emphasis is on the basic morphology with newer techniques represented where they are frequently used. The series provides a handy summary and quick reference that any pathology resident or fellow will find useful. Experienced practitioners will find the series valuable as a portable "refresher course" or review tool. Lymph Nodes presents the full gamut of lymph node disorders and diagnoses that pathologists commonly see in practice. Traditional morphology and histopathologic features, coupled with clinical data, are emphasized. Chapters are complemented with both high-power images for analysis of cytologic features of lymph node cells as well as low-power images for assessment of lymph node architecture. The chapters cover infectious lymphadenopathies, reactive lymphadenopathies, lymphadenopathies associated with systemic disorders, lymph node inclusions, spindle cell neoplasms of lymph nodes, foreign body lymphadenopathies, mature B-cell neoplasms, precursor lymphoid neoplasms, Hodgkin lymphoma, and more. Lymph Nodes is highly illustrated throughout and provides residents and clinicians with a quick reference for rotation or review.

Neoplastic Hematopathology

An Atlas and Concise Guide

Author: Cherie H. Dunphy, MD

Publisher: Demos Medical Publishing

ISBN: 1617051101

Category: Medical

Page: 348

View: 6913

Neoplastic Hematopathology provides a concise, visual approach to guide practicing pathologists, hematopathologists, hematologists, oncologists, internists, and trainees to a clear analysis and diagnosis of myeloid and lymphoid specimens. Coverage is comprehensive and for each entity includes a short text description of the key points of the entity- definition; morphologic features; special stains, immunohistochemistry and flow cytometry techniques; differential diagnosis; diagnostic features; special issues (e.g., prognostic or other considerations to note). Images in Neoplastic Hematopathology highlight differential diagnostic features, especially the correlation and integration of standard H & E stains with molecular and immunologic techniques. Neoplastic Hematopathology: An Atlas and Concise Guide features: Clear, concise coverage across the wide range of hematopathologic entities based on the current World Health Organization (WHO) classification Topics selected on the basis of "must-know" entities for the practicing pathologist or trainee Emphasis on integration of routine and special stains with immunologic and molecular techniques, reflecting the most current standards of practice Outstanding images selected to highlight key differential points and potentially misleading variants

Hematopoietic Neoplasms: Controversies in Diagnosis and Classification, An Issue of Surgical Pathology Clinics,

Author: Tracey I George

Publisher: Elsevier Health Sciences

ISBN: 032327787X

Category: Medical

Page: 209

View: 9411

Topics in Hematopoietic Neoplasms: Controversies in Diagnosis and Classification include: ABC vs GC subtyping of diffuse large B cell lymphoma-Does it matter?; Clonal link between malignant lymphoma and histiocytic tumors; Diagnostic criteria for grey zone lymphoma: Are there any?; Diagnostic criteria for primary cutaneous B cell lymphoma; Distinguishing reactive and leukemic large granular lymphocyte proliferations; Differential diagnosis of erythroleukemia; Early pre-T ALL versus MPAL: Diagnostic criteria; Myeloid neoplasms with inv(3) or t(3;3); Update on classification and prognosis in myelodysplastic syndrome; Approach to atypical immunophenotypes in Hodgkin lymphoma; Blastic plasmacytoid dendritic cell tumor: How do you distinguish it from acute myeloid leukemia?; The differential diagnosis of eosinophilia in neoplastic hematopathology; Transformation in myeloproliferative neoplasms; and Challenges in consolidated reporting of hematopoietic neoplasms. This publication is an extremely useful and practical source for pathologists working with this spectrum of disorders. As with all publications in this series, Differential Diagnosis is the main focus of discussion. Staging, Diagnosis, Prognosis, and summaries of Pitfalls in working with these pathologies are presented along with ample figures.

Molecular Basis of Chronic Myeloproliferative Disorders

Author: P.E. Petrides

Publisher: Springer Science & Business Media

ISBN: 3642187382

Category: Medical

Page: 218

View: 3115

Since the first description of Philadelphia chromosome-negative chronic myeloproliferative disorders more than 100 years ago, the diagnosis and therapy of these conditions have been based primarily on clinical experience and judgement. Until recently very little was known about the molecular basis of these diseases. In order to spark research in this area basic scientists and clinicians from various parts of the world have contributed to this volume, the first of its kind to put together the current knowledge. The book deals with the new WHO classification of these disorders, novel aspects of diagnostic pathology, the search for disease-relevant genes utilizing molecular biology and proteomic techniques, the description of the roles of PVR-1 and VHL genes for polycythemias and the discovery of the gene mutation responsible for the idiopathic hypereosinophilic syndrome. A chapter on anagrelide, an important novel drug for the treatment of primary thrombocythemia, is included.

The Diagnosis of Lymphoproliferative Diseases

Author: Kevin Gatter,Georges Delsol,Roger Warnke,Francesco Pezzella

Publisher: John Wiley & Sons

ISBN: 1119971756

Category: Medical

Page: 280

View: 9799

This highly illustrated, diagnostic guidebook provides a single comprehensive source of essential information to enable non-specialists to diagnose lymph node and related diseases with confidence. The text is didactic and practical, covering reactive as well as malignant conditions. Diagnosis of Lymphoproliferative Diseases approaches the disorders based on the WHO classification and is edited by members of the WHO panel for the classification of lymphomas. This second edition contains over 1000 high quality, digitised colour images and tables of essential criteria for each diagnosis. New features include: Full discussion of immunostaining, the core of modern diagnosis Variant forms and technical issues This authoritative guide is an essential reference for haematologists, haematopathologists, general pathologists, diagnostic histopathologists and oncologists.

Comprehensive Cytopathology E-Book

Author: Marluce Bibbo,David Wilbur

Publisher: Elsevier Health Sciences

ISBN: 1437719627

Category: Medical

Page: 1136

View: 2159

This best-selling book provides you with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and covers the recognized normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is lavishly illustrated, making it the perfect practical resource for daily reference in the laboratory. Provides an accessible guide to diagnostic investigation and screening. Includes a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Utilizes a consistent chapter structure to make finding the answers you need quick and easy. Provides updates to crucial chapters to keep you on top of the latest diagnosis and techniques. Incorporates differential diagnosis tables for easy comparison/contrast of diagnoses. Offers more than 1800 full-color images depicting a full range of normal and abnormal findings. Discusses new concepts on molecular basis of neoplasia. Explores the role of cytogenetics in cancer development.

Diagnostic Histopathology of Tumors

Author: Christopher D. M. Fletcher

Publisher: Elsevier Health Sciences

ISBN: 1455737542

Category: Medical

Page: 2296

View: 7319

Diagnose tumors with confidence with Diagnostic Histopathology of Tumors, 4th Edition. Dr. Christopher Fletcher's renowned reference provides the advanced, expert guidance you need to evaluate and interpret even the most challenging histopathology specimens more quickly and accurately. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Diagnose efficiently and effectively using diagnostic flow charts, correlations of gross appearances to microscopic findings, and differential diagnosis tables for better recognition and evaluation of similar-looking entities. Employ immunohistochemistry, molecular and genetic diagnostic tests, and other modern techniques as well as the best morphologic diagnostic methods to effectively identify each tumor or tumor-like entity. Utilize new, clinically important molecular genetic data and updated classification schemes to help guide treatment and targeted therapy. Apply the latest techniques and diagnostic criteria with completely rewritten chapters on Small and Large Intestines, Heart, Larynx and Trachea, Ear, and Peritoneum. Find critical information quickly thanks to more tables and bulleted lists throughout.

Blood and Bone Marrow Pathology E-Book

Author: Anna Porwit,Jeffrey McCullough,Wendy N Erber

Publisher: Elsevier Health Sciences

ISBN: 0702045357

Category: Medical

Page: 722

View: 9157

Chapters have been totally rewritten and some new chapters have been added especially on myeloid malignancies, in line with the WHO 2008 Classification All chapters have been revised to include new aspects of molecular biology and updated concerning flow cytometry diagnostics Greater emphasis on practical diagnostic aspects for all disorders Brand new editorial and contributing author team. Full Online text through Expert Consult. Full downloadable Image Bank

Mastocytosis, An Issue of Immunology and Allergy Clinics,

Author: Cem Akin

Publisher: Elsevier Health Sciences

ISBN: 0323297102

Category: Medical

Page: 281

View: 9389

This issue of Immunology and Allergy Clinics, edited by Dr. Cem Akin, is devoted to Mastocytosis. Articles in this issue include Human Mast Cell Signal Transduction; Mast cell tryptase role in homeostasis and coagulation; Mastocytosis: Current Classification and Diagnostic criteria; Epidemiology, risk factors and prognosis of mastocytosis; Mast cell sarcoma: Clinical management; Molecular defects in mastocytosis: c-kit mutations and beyond; Flow cytometry in mastocytosis: Utility as a diagnostic and prognostic tool; Morphology of mastocytosis with special reference to immunophenotypical aberrancies; CD30 expression in mastocytosis; Extramedullary mastocytosis: Pathologic aspects; Bone involvement and osteoporosis in mastocytosis; Drug allergy in mastocytosis; Eosinophilia in mastocytosis; Venom allergy and mastocytosis; Skin disease in mastocytosis; Treatment of advanced mastocytosis; Treatment strategies of mediator related symptoms in mastocytosis; and Neuro and psychological involvement in Mastocytosis.

Molecular Oncology, An Issue of Surgical Pathology Clinics - E-Book

Author: Jennifer Hunt

Publisher: Elsevier Health Sciences

ISBN: 1455750530

Category: Medical

Page: 240

View: 1420

Clinically accessible information for pathologists on the fast moving field of molecular pathology and oncology, addressing molecular and genetic approaches to the diagnosis and classification of tumors, predictive biomarkers for treatment response and disease progression. Recurrent in this series, summaries are provided of Key Features of tumor, Key molecular prognostic markers and therapeutic markers, Tumor suppressor genes, and Oncogenes. Topics include molecular pathology of: Breast, Gastrointestinal, Head and Neck, Genitourinary, Gynecologic, Hematopathology, Lung, Neuropathology, Pancreas/Biliary, and Sarcome.

Klassifikation maligner Tumoren des Gastrointestinaltrakts II

Author: Peter J. Neuhaus,Christian F. Wittekind

Publisher: Springer-Verlag

ISBN: 3540498214

Category: Medical

Page: 385

View: 3921

Nach den neuesten (inter)nationalen Standards: In Band 2 beschreiben die Autoren die Histomorphologie (Typing and Grading) und die anatomische Ausbreitung vor und nach der Therapie (TNM und R-Klassifikation). Zusätzlich thematisieren sie die Diagnose, Therapie und Prognosefaktoren der malignen Tumore von Leber, Gallenblase, Gallengängen, Ampulla Vateri und Pankreas. Band 2 ergänzt Band 1 um die malignen Tumoren von Ösophagus, ösophagogastralem Übergang, Magen, Dünndarm, Appendix, Kolon, Rektum und Analkanal. Ein überaus handliches Buch und ausführliches Nachschlagewerk zur Stadieneinteilung gastrointestinaler Tumore für Ärzte.

Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book

Author: Richard A. McPherson,Matthew R. Pincus

Publisher: Elsevier Health Sciences

ISBN: 1455726842

Category: Medical

Page: 1568

View: 7979

Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.

Atlas of Lymph Node Pathology

Author: Roberto N. Miranda,Joseph D. Khoury,L. Jeffrey Medeiros

Publisher: Springer Science & Business Media

ISBN: 1461479592

Category: Medical

Page: 530

View: 5979

Atlas of Lymph Node Pathology reviews the histopathology of nodal diseases, illustrating the use of ancillary studies and includes concise discussions of pathogenesis, clinical settings and clinical significance of the pathologic diagnosis. The atlas features an overview of the benign reactive processes secondary to infectious, environmental or unknown insults, as well as relevant illustrations of virtually all primary and secondary neoplasms involving lymph nodes. The atlas also includes macroscopic images of some disorders, tables that help readers understand and comprehend diseases that look alike, and diagnostic algorithms for certain groups of diseases. Authored by highly experienced pathologists, Atlas of Lymph Node Pathology is a valuable resource that illustrates the vast majority of diseases practicing pathologists, clinicians and oncologists are likely to encounter in daily practice.